(data stored in ACNUC7421 zone)

SWISSPROT: C4KK50_SULIK

ID   C4KK50_SULIK            Unreviewed;       357 AA.
AC   C4KK50;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 47.
DE   RecName: Full=Peptide chain release factor subunit 1 {ECO:0000256|HAMAP-Rule:MF_00424};
DE   AltName: Full=Translation termination factor aRF1 {ECO:0000256|HAMAP-Rule:MF_00424};
GN   Name=prf1 {ECO:0000256|HAMAP-Rule:MF_00424};
GN   OrderedLocusNames=M164_0157 {ECO:0000313|EMBL:ACR40791.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR40791.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR40791.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: Directs the termination of nascent peptide synthesis
CC       (translation) in response to the termination codons UAA, UAG and
CC       UGA. {ECO:0000256|HAMAP-Rule:MF_00424}.
CC   -!- SUBUNIT: Heterodimer of two subunits, one of which binds GTP.
CC       {ECO:0000256|HAMAP-Rule:MF_00424}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00424}.
CC   -!- SIMILARITY: Belongs to the eukaryotic release factor 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00424}.
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DR   EMBL; CP001402; ACR40791.1; -; Genomic_DNA.
DR   RefSeq; WP_012710316.1; NC_012726.1.
DR   EnsemblBacteria; ACR40791; ACR40791; M164_0157.
DR   GeneID; 7813831; -.
DR   KEGG; sid:M164_0157; -.
DR   HOGENOM; HOG000224682; -.
DR   KO; K03265; -.
DR   OMA; QNFITAD; -.
DR   OrthoDB; POG093Z03S1; -.
DR   BioCyc; SISL426118:GI01-159-MONOMER; -.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.30.960.10; -; 1.
DR   HAMAP; MF_00424; Rel_fact_arch_1; 1.
DR   InterPro; IPR005140; eRF1_1_Pelota.
DR   InterPro; IPR005141; eRF1_2.
DR   InterPro; IPR005142; eRF1_3.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR020918; Peptide_chain-rel_aRF1.
DR   InterPro; IPR004403; Peptide_chain-rel_eRF1/aRF1.
DR   InterPro; IPR024049; Release_factor_eRF1/aRF1_N.
DR   PANTHER; PTHR10113; PTHR10113; 1.
DR   Pfam; PF03464; eRF1_2; 1.
DR   Pfam; PF03465; eRF1_3; 1.
DR   SMART; SM01194; eRF1_1; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF55481; SSF55481; 1.
DR   TIGRFAMs; TIGR03676; aRF1/eRF1; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KK50.
DR   SWISS-2DPAGE; C4KK50.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00424};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00424}.
FT   DOMAIN        1    122       eRF1_1. {ECO:0000259|SMART:SM01194}.
SQ   SEQUENCE   357 AA;  40957 MW;  30647DDD92B3DDC2 CRC64;
     MKALIKELKK WKAPATVLLS LYIPPGRPIP DVVNLLRQEY SIAQNIKLKR TRDAVLSAIG
     AAIDRLNKIP KIDGNGLVLF CGENFDTEDF KCFMFSPPDK VPLFFYRTDK EFHVEFLEDM
     VEDTVVYGLI IVERDEATIG LLKGTRIEIL EEIEGFVPGK HMMGGQSQRR IDRIIDEMYH
     NFLKEVGEKV NAYFMPFIQT GKMKGILLGG PGYAKEDFYK EDYVDYRIKN LILQPLIDVS
     DQGEVGLREM IMRAEDLLKN QQYVEVEKLL EELKYHLAKD DGLIIYGKEQ IKKAMEMGAV
     EAIVIHEDSS DKELEKLAQD AENYGVKVFV VGDEVPEAEW VKKTFNGVVG KLRYRLY
//

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