(data stored in ACNUC7421 zone)

SWISSPROT: C4KKZ9_SULIK

ID   C4KKZ9_SULIK            Unreviewed;       314 AA.
AC   C4KKZ9;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   30-AUG-2017, entry version 47.
DE   SubName: Full=Aryldialkylphosphatase {ECO:0000313|EMBL:ACR40964.1};
DE            EC=3.1.8.1 {ECO:0000313|EMBL:ACR40964.1};
GN   OrderedLocusNames=M164_0332 {ECO:0000313|EMBL:ACR40964.1};
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR40964.1, ECO:0000313|Proteomes:UP000001479};
RN   [1] {ECO:0000313|EMBL:ACR40964.1, ECO:0000313|Proteomes:UP000001479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
RN   [2] {ECO:0000213|PDB:4G2D}
RP   X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) IN COMPLEX WITH IRON.
RX   PubMed=23071703; DOI=10.1371/journal.pone.0047028;
RA   Hiblot J., Gotthard G., Chabriere E., Elias M.;
RT   "Structural and enzymatic characterization of the lactonase SisLac
RT   from Sulfolobus islandicus.";
RL   PLoS ONE 7:e47028-e47028(2012).
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|PIRSR:PIRSR601559-51};
CC       Note=Binds 2 divalent metal cations per subunit.
CC       {ECO:0000256|PIRSR:PIRSR601559-51};
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DR   EMBL; CP001402; ACR40964.1; -; Genomic_DNA.
DR   RefSeq; WP_012710474.1; NC_012726.1.
DR   PDB; 4G2D; X-ray; 2.70 A; A=1-314.
DR   PDBsum; 4G2D; -.
DR   ProteinModelPortal; C4KKZ9; -.
DR   SMR; C4KKZ9; -.
DR   EnsemblBacteria; ACR40964; ACR40964; M164_0332.
DR   GeneID; 7813195; -.
DR   KEGG; sid:M164_0332; -.
DR   HOGENOM; HOG000081700; -.
DR   KO; K07048; -.
DR   OMA; PFQIIRV; -.
DR   OrthoDB; POG093Z09MD; -.
DR   BioCyc; SISL426118:GI01-334-MONOMER; -.
DR   BRENDA; 3.1.1.2; 8240.
DR   BRENDA; 3.1.1.25; 8240.
DR   BRENDA; 3.1.8.1; 8240.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0004063; F:aryldialkylphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009056; P:catabolic process; IEA:InterPro.
DR   CDD; cd00530; PTE; 1.
DR   InterPro; IPR017947; AryldialkylPase_Zn-BS.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR001559; Phosphotriesterase.
DR   PANTHER; PTHR10819; PTHR10819; 1.
DR   Pfam; PF02126; PTE; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
DR   PROSITE; PS01322; PHOSPHOTRIESTERASE_1; 1.
DR   PROSITE; PS51347; PHOSPHOTRIESTERASE_2; 1.
PE   1: Evidence at protein level;
DR   PRODOM; C4KKZ9.
DR   SWISS-2DPAGE; C4KKZ9.
KW   3D-structure {ECO:0000213|PDB:4G2D};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001479};
KW   Hydrolase {ECO:0000313|EMBL:ACR40964.1}; Iron {ECO:0000213|PDB:4G2D};
KW   Metal-binding {ECO:0000213|PDB:4G2D, ECO:0000256|PIRSR:PIRSR601559-
KW   51}.
FT   METAL        22     22       Divalent metal cation 1; via tele
FT                                nitrogen. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL        22     22       Iron; via tele nitrogen.
FT                                {ECO:0000213|PDB:4G2D}.
FT   METAL        24     24       Divalent metal cation 1; via tele
FT                                nitrogen. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL        24     24       Iron; via tele nitrogen.
FT                                {ECO:0000213|PDB:4G2D}.
FT   METAL       137    137       Divalent metal cation 1; via carbamate
FT                                group. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL       137    137       Divalent metal cation 2; via carbamate
FT                                group. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL       137    137       Iron. {ECO:0000213|PDB:4G2D}.
FT   METAL       170    170       Divalent metal cation 2; via pros
FT                                nitrogen. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL       199    199       Divalent metal cation 2; via tele
FT                                nitrogen. {ECO:0000256|PIRSR:PIRSR601559-
FT                                51}.
FT   METAL       256    256       Divalent metal cation 1.
FT                                {ECO:0000256|PIRSR:PIRSR601559-51}.
FT   MOD_RES     137    137       N6-carboxylysine. {ECO:0000256|PIRSR:
FT                                PIRSR601559-50}.
SQ   SEQUENCE   314 AA;  35606 MW;  0C0C63800638BF7A CRC64;
     MRIPLVGKEP IEAEDMGFTL IHEHLRVFSE AVRYQWPHLY NEDEELRNAV NEVKRAMQFG
     VKTIVDPTVM GLGRDIRFME KVVKTTGINL VAGTGIYIYV DLPFYFLNRS IDEIADLFIH
     DIKEGIQATS NKAGFVKIAA DEPGITKDVE KVIRAAAITH KEAKVPIITH SNAHNNTGLE
     EQRILMEEGV DPGKILIGHL GDTDNTDYIK KIADKGSFIG LDRYGLDLFL PVDKRNETTL
     KLIKDGYSDR IMISHDYCCT IDWGTARPEL KPKLAPRWSM ALIFEDTIPF LKKNGVSEEV
     IDIIFKENPK KFFS
//

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