(data stored in ACNUC7421 zone)

SWISSPROT: DNAA_EDWI9

ID   DNAA_EDWI9              Reviewed;         463 AA.
AC   C5BHC5;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 54.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=NT01EI_0001;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001600; ACR67263.1; -; Genomic_DNA.
DR   ProteinModelPortal; C5BHC5; -.
DR   SMR; C5BHC5; -.
DR   STRING; 634503.NT01EI_0001; -.
DR   EnsemblBacteria; ACR67263; ACR67263; NT01EI_0001.
DR   KEGG; eic:NT01EI_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BHC5.
DR   SWISS-2DPAGE; C5BHC5.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    463       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000205651.
FT   NP_BIND     168    175       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   463 AA;  52054 MW;  705E4EBA2523260B CRC64;
     MSLSLWQQCL ARLQDELPAT EFSMWIRPLQ AELSDNTLAL YAPNRFVLDW VRDKYINNIN
     GLLNDFCGSD APVLRFEVGS KPIVPVAVSS AASSGASVPP AAVRASSLAR PSWERVTAQP
     ELSYRSNVNP KHTFDNFVEG KSNQLARAAA RQVADNPGGA YNPLFLYGGT GLGKTHLLHA
     VGNGIMARKP NAKVVYMHSE RFVQDMVKAL QNNAIEEFKR YYRSVDALLI DDIQFFANKE
     RSQEEFFHTF NALLEGNQQI ILTSDRYPKE INGVEDRLKS RFGWGLTVAI EPPELETRVA
     ILMKKADEND IRLPGEVAFF IAKRLRSNVR ELEGALNRVI ANANFTGRAI TIDFVREALR
     DLLALQEKLV TIDNIQKTVA EYYKIKVADL LSKRRSRSVA RPRQMAMALA KELTNHSLPE
     IGDAFGGRDH TTVLHACRKI EQLREESHDI KEDFSNLIRT LSS
//

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