(data stored in ACNUC7421 zone)

SWISSPROT: SLMA_EDWI9

ID   SLMA_EDWI9              Reviewed;         198 AA.
AC   C5B9D1;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 53.
DE   RecName: Full=Nucleoid occlusion factor SlmA {ECO:0000255|HAMAP-Rule:MF_01839};
GN   Name=slmA {ECO:0000255|HAMAP-Rule:MF_01839};
GN   OrderedLocusNames=NT01EI_0051;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for nucleoid occlusion (NO) phenomenon, which
CC       prevents Z-ring formation and cell division over the nucleoid.
CC       Acts as a DNA-associated cell division inhibitor that binds
CC       simultaneously chromosomal DNA and FtsZ, and disrupts the assembly
CC       of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed
CC       on non-Ter regions of the chromosome, preventing FtsZ
CC       polymerization at these regions. {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SIMILARITY: Belongs to the nucleoid occlusion factor SlmA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01839}.
DR   EMBL; CP001600; ACR67311.1; -; Genomic_DNA.
DR   RefSeq; WP_015869535.1; NC_012779.2.
DR   ProteinModelPortal; C5B9D1; -.
DR   SMR; C5B9D1; -.
DR   STRING; 634503.NT01EI_0051; -.
DR   PRIDE; C5B9D1; -.
DR   EnsemblBacteria; ACR67311; ACR67311; NT01EI_0051.
DR   GeneID; 7959770; -.
DR   KEGG; eic:NT01EI_0051; -.
DR   PATRIC; fig|634503.3.peg.44; -.
DR   eggNOG; ENOG4105EC0; Bacteria.
DR   eggNOG; COG1309; LUCA.
DR   HOGENOM; HOG000266053; -.
DR   KO; K05501; -.
DR   OMA; IEQTVFG; -.
DR   OrthoDB; POG091H068M; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0010974; P:negative regulation of barrier septum assembly; IEA:InterPro.
DR   HAMAP; MF_01839; NO_factor_SlmA; 1.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR023769; NO_SlmA.
DR   InterPro; IPR011075; Tet_transcr_reg_TetR-rel_C.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF48498; SSF48498; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5B9D1.
DR   SWISS-2DPAGE; C5B9D1.
KW   Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm;
KW   DNA-binding; Reference proteome.
FT   CHAIN         1    198       Nucleoid occlusion factor SlmA.
FT                                /FTId=PRO_1000216092.
FT   DOMAIN        9     70       HTH tetR-type. {ECO:0000255|HAMAP-
FT                                Rule:MF_01839}.
FT   DNA_BIND     33     52       H-T-H motif. {ECO:0000255|HAMAP-
FT                                Rule:MF_01839}.
FT   COILED      117    144       {ECO:0000255|HAMAP-Rule:MF_01839}.
SQ   SEQUENCE   198 AA;  23158 MW;  3FC1513828CCF53F CRC64;
     MAEKENTKRN RREEILQALA QMLESSDGSQ RITTAKLAAN VGVSEAALYR HFPSKTRMFD
     SLIEFIEDTL TSRINLILQD EKDTFHRLRL ILLLILGFAE RNPGLTRIMT GHALMFEQDR
     LQGRINQLFE RIEAQLRQVL KERRLREGSG FDHDETLLAS QLLAFCEGML SRFVRSEFRY
     RPTQEFETRW PLLACQLQ
//

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