(data stored in ACNUC7421 zone)

SWISSPROT: C5BHD9_EDWI9

ID   C5BHD9_EDWI9            Unreviewed;       181 AA.
AC   C5BHD9;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 63.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000256|HAMAP-Rule:MF_00948, ECO:0000256|RuleBase:RU000538, ECO:0000256|SAAS:SAAS00126873};
GN   Name=nusG {ECO:0000256|HAMAP-Rule:MF_00948};
GN   OrderedLocusNames=NT01EI_0169 {ECO:0000313|EMBL:ACR67417.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67417.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in transcription elongation, termination
CC       and antitermination. In the absence of Rho, increases the rate of
CC       transcription elongation by the RNA polymerase (RNAP), probably by
CC       partially suppressing pausing. In the presence of Rho, modulates
CC       most Rho-dependent termination events by interacting with the RNAP
CC       to render the complex more susceptible to the termination activity
CC       of Rho. May be required to overcome a kinetic limitation of Rho to
CC       function at certain terminators. Also involved in ribosomal RNA
CC       transcriptional antitermination. {ECO:0000256|HAMAP-
CC       Rule:MF_00948}.
CC   -!- SUBUNIT: Monomer. Interacts with the transcription termination
CC       factor Rho and with RNA polymerase. {ECO:0000256|HAMAP-
CC       Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00948, ECO:0000256|RuleBase:RU000538,
CC       ECO:0000256|SAAS:SAAS00565689}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001600; ACR67417.1; -; Genomic_DNA.
DR   RefSeq; WP_015869631.1; NC_012779.2.
DR   STRING; 634503.NT01EI_0169; -.
DR   EnsemblBacteria; ACR67417; ACR67417; NT01EI_0169.
DR   GeneID; 7958762; -.
DR   KEGG; eic:NT01EI_0169; -.
DR   PATRIC; fig|634503.3.peg.152; -.
DR   eggNOG; ENOG4105E5V; Bacteria.
DR   eggNOG; COG0250; LUCA.
DR   HOGENOM; HOG000219264; -.
DR   KO; K02601; -.
DR   OMA; DGPFNGF; -.
DR   OrthoDB; POG091H02IB; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like.
DR   PANTHER; PTHR30265:SF4; PTHR30265:SF4; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR00922; nusG; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BHD9.
DR   SWISS-2DPAGE; C5BHD9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00948,
KW   ECO:0000256|RuleBase:RU000538, ECO:0000256|SAAS:SAAS00126904};
KW   Transcription antitermination {ECO:0000256|HAMAP-Rule:MF_00948,
KW   ECO:0000256|RuleBase:RU000538, ECO:0000256|SAAS:SAAS00454500};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00948,
KW   ECO:0000256|RuleBase:RU000538, ECO:0000256|SAAS:SAAS00481954};
KW   Transcription termination {ECO:0000256|HAMAP-Rule:MF_00948,
KW   ECO:0000256|RuleBase:RU000538, ECO:0000256|SAAS:SAAS00078462}.
FT   DOMAIN        6    115       NGN. {ECO:0000259|SMART:SM00738}.
FT   DOMAIN      127    154       KOW. {ECO:0000259|SMART:SM00739}.
SQ   SEQUENCE   181 AA;  20601 MW;  D6849677FAF648E0 CRC64;
     MSEAPKKRWY VVQAFSGFEG RVAQSLREHI KLHNMEELFG EVMVPTEEVV EIRGGQRRKS
     ERKFFPGYVL VQMVMNDASW HLVRSVPRVM GFIGGTSDRP APISDKEVDA IMNRLQQIGD
     KPRPKTLFEP GEMVRVNEGP FADFNGVVEE VDYEKSRLKV SVSIFGRATP VELDFSQVEK
     A
//

If you have problems or comments...

PBIL Back to PBIL home page