(data stored in ACNUC7421 zone)

SWISSPROT: G6PI_EDWI9

ID   G6PI_EDWI9              Reviewed;         549 AA.
AC   C5B6Z1;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   30-AUG-2017, entry version 49.
DE   RecName: Full=Glucose-6-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_00473};
DE            Short=GPI {ECO:0000255|HAMAP-Rule:MF_00473};
DE            EC=5.3.1.9 {ECO:0000255|HAMAP-Rule:MF_00473};
DE   AltName: Full=Phosphoglucose isomerase {ECO:0000255|HAMAP-Rule:MF_00473};
DE            Short=PGI {ECO:0000255|HAMAP-Rule:MF_00473};
DE   AltName: Full=Phosphohexose isomerase {ECO:0000255|HAMAP-Rule:MF_00473};
DE            Short=PHI {ECO:0000255|HAMAP-Rule:MF_00473};
GN   Name=pgi {ECO:0000255|HAMAP-Rule:MF_00473};
GN   OrderedLocusNames=NT01EI_0210;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate. {ECO:0000255|HAMAP-Rule:MF_00473}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00473}.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC       {ECO:0000255|HAMAP-Rule:MF_00473}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00473}.
CC   -!- SIMILARITY: Belongs to the GPI family. {ECO:0000255|HAMAP-
CC       Rule:MF_00473}.
DR   EMBL; CP001600; ACR67453.1; -; Genomic_DNA.
DR   RefSeq; WP_015869663.1; NC_012779.2.
DR   SMR; C5B6Z1; -.
DR   STRING; 634503.NT01EI_0210; -.
DR   PRIDE; C5B6Z1; -.
DR   EnsemblBacteria; ACR67453; ACR67453; NT01EI_0210.
DR   GeneID; 7958798; -.
DR   KEGG; eic:NT01EI_0210; -.
DR   PATRIC; fig|634503.3.peg.186; -.
DR   eggNOG; ENOG4107QP8; Bacteria.
DR   eggNOG; COG0166; LUCA.
DR   HOGENOM; HOG000261370; -.
DR   KO; K01810; -.
DR   OMA; TNSQHAF; -.
DR   OrthoDB; POG091H04C3; -.
DR   UniPathway; UPA00109; UER00181.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd05015; SIS_PGI_1; 1.
DR   CDD; cd05016; SIS_PGI_2; 1.
DR   Gene3D; 1.10.1390.10; -; 1.
DR   HAMAP; MF_00473; G6P_isomerase; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR023096; G6P_Isomerase_C.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   InterPro; IPR035476; SIS_PGI_1.
DR   InterPro; IPR035482; SIS_PGI_2.
DR   PANTHER; PTHR11469; PTHR11469; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
DR   PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5B6Z1.
DR   SWISS-2DPAGE; C5B6Z1.
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase;
KW   Reference proteome.
FT   CHAIN         1    549       Glucose-6-phosphate isomerase.
FT                                /FTId=PRO_1000206365.
FT   ACT_SITE    386    386       {ECO:0000255|HAMAP-Rule:MF_00473}.
FT   ACT_SITE    514    514       {ECO:0000255|HAMAP-Rule:MF_00473}.
SQ   SEQUENCE   549 AA;  61432 MW;  657972086A3D2C79 CRC64;
     MKNINPTRTA AWQALQQHFG QMKSVHMRDL FAADADRFSK FSATFDDQML VDYSKNRINA
     ETLEKLQALA RETDLQGAIA AMFAGEKINR TEDRAVLHIA LRNRSNTPIC VDGKDVMPEV
     NAVLAKMKQF CVRVIDGEWR GYTGKAITDV VNIGIGGSDL GPYMVTEALR PYKNHLTMHF
     VSNVDGTHIA ETLQRLNPET TLFLVASKTF TTQETMTNAH SARDWFLQAA GDERHVARHF
     AALSTNVQAV AAFGIDTANM FEFWDWVGGR YSLWSAIGLS IALSIGYDNF EQLLAGAHAM
     DRHFASAPLP QNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFPAYFQ QGNMESNGKY
     VDRDGQVVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLIP CDFIAPAISH NPLGDHHGKL
     LSNFFAQTEA LAFGKSREAV EEEFAKAGKS AAEVQHIVPF KVFEGNRPTN SILLREITPY
     SLGMLIALYE HKIFTQGVIL NIFSFDQWGV ELGKQLANRI LPELEDAQPV RSHDSSTNAL
     INRFKAWRA
//

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