(data stored in ACNUC7421 zone)

SWISSPROT: C5B724_EDWI9

ID   C5B724_EDWI9            Unreviewed;       470 AA.
AC   C5B724;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 61.
DE   RecName: Full=Replicative DNA helicase {ECO:0000256|RuleBase:RU362085};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU362085};
GN   OrderedLocusNames=NT01EI_0243 {ECO:0000313|EMBL:ACR67486.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67486.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in initiation and elongation during
CC       chromosome replication; it exhibits DNA-dependent ATPase activity
CC       and contains distinct active sites for ATP binding, DNA binding,
CC       and interaction with DnaC protein, primase, and other prepriming
CC       proteins. {ECO:0000256|RuleBase:RU362085}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|RuleBase:RU362085}.
CC   -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC       {ECO:0000256|RuleBase:RU362085}.
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DR   EMBL; CP001600; ACR67486.1; -; Genomic_DNA.
DR   RefSeq; WP_015869695.1; NC_012779.2.
DR   ProteinModelPortal; C5B724; -.
DR   STRING; 634503.NT01EI_0243; -.
DR   EnsemblBacteria; ACR67486; ACR67486; NT01EI_0243.
DR   GeneID; 7960024; -.
DR   KEGG; eic:NT01EI_0243; -.
DR   PATRIC; fig|634503.3.peg.219; -.
DR   eggNOG; ENOG4105CDU; Bacteria.
DR   eggNOG; COG0305; LUCA.
DR   HOGENOM; HOG000113196; -.
DR   KO; K02314; -.
DR   OMA; FQIAEAR; -.
DR   OrthoDB; POG091H023D; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR   CDD; cd00984; DnaB_C; 1.
DR   Gene3D; 1.10.860.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR007692; DNA_helicase_DnaB.
DR   InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR   InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR   InterPro; IPR016136; DNA_helicase_N/primase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00772; DnaB; 1.
DR   Pfam; PF03796; DnaB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48024; SSF48024; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00665; DnaB; 1.
DR   PROSITE; PS51199; SF4_HELICASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5B724.
DR   SWISS-2DPAGE; C5B724.
KW   ATP-binding {ECO:0000256|RuleBase:RU362085};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   DNA replication {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740714};
KW   DNA-binding {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740674};
KW   Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:ACR67486.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000313|EMBL:ACR67486.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362085};
KW   Primosome {ECO:0000256|RuleBase:RU362085};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485}.
FT   DOMAIN      198    465       SF4 helicase. {ECO:0000259|PROSITE:
FT                                PS51199}.
SQ   SEQUENCE   470 AA;  52772 MW;  D000886990696BA7 CRC64;
     MAGNNPSSKS REAPRDRQME GLKLPPHSLE AEQSVLGGLM LDNERWDHVA ERVVSNDFYS
     RPHRLIFGEM QRLLELGRPI DLITLSESLE QLGHLESVGG FAYLAELSKN TPSAANINAY
     ADIVRERAVV REMITVANEI ADAGYDPQGR SSEDLLDLAE SRVFQIAENR ASKDEGPKSI
     DRILEDTVSR IEQLYQRPHD GVTGVSTGYQ DLDKKTAGLQ KSDLIIVAAR PSMGKTTFAM
     NLCENAAMTQ DKPVLIFSLE MPGEQIMMRM LASLSRVDQT RIRTGQLDDE DWARISSTMG
     LLLEKRNMYI DDSSGLTPTE VRSRARRIFR EHDGLSLIMI DYLQLMRVPS LSDNRTLEIA
     EISRSLKALA KELQVPVVAL SQLNRSLEQR ADKRPVNSDL RESGSIEQDA DLIMFIYRDE
     VYHENSDLKG VAEIILGKQR NGPIGTVRLT FNGQWSRFDN YAGPAYSDED
//

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