(data stored in ACNUC7421 zone)

SWISSPROT: C5BCV3_EDWI9

ID   C5BCV3_EDWI9            Unreviewed;       456 AA.
AC   C5BCV3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 60.
DE   RecName: Full=Replicative DNA helicase {ECO:0000256|RuleBase:RU362085};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU362085};
GN   OrderedLocusNames=NT01EI_0317 {ECO:0000313|EMBL:ACR67559.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67559.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in initiation and elongation during
CC       chromosome replication; it exhibits DNA-dependent ATPase activity
CC       and contains distinct active sites for ATP binding, DNA binding,
CC       and interaction with DnaC protein, primase, and other prepriming
CC       proteins. {ECO:0000256|RuleBase:RU362085}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|RuleBase:RU362085}.
CC   -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC       {ECO:0000256|RuleBase:RU362085}.
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DR   EMBL; CP001600; ACR67559.1; -; Genomic_DNA.
DR   RefSeq; WP_015869766.1; NC_012779.2.
DR   ProteinModelPortal; C5BCV3; -.
DR   STRING; 634503.NT01EI_0317; -.
DR   EnsemblBacteria; ACR67559; ACR67559; NT01EI_0317.
DR   GeneID; 7960098; -.
DR   KEGG; eic:NT01EI_0317; -.
DR   PATRIC; fig|634503.3.peg.285; -.
DR   eggNOG; ENOG4105CDU; Bacteria.
DR   eggNOG; COG0305; LUCA.
DR   HOGENOM; HOG000113196; -.
DR   KO; K02314; -.
DR   OMA; EIYDNAG; -.
DR   OrthoDB; POG091H023D; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR   CDD; cd00984; DnaB_C; 1.
DR   Gene3D; 1.10.860.10; -; 1.
DR   InterPro; IPR007692; DNA_helicase_DnaB.
DR   InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR   InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR   InterPro; IPR016136; DNA_helicase_N/primase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00772; DnaB; 1.
DR   Pfam; PF03796; DnaB_C; 1.
DR   SUPFAM; SSF48024; SSF48024; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00665; DnaB; 1.
DR   PROSITE; PS51199; SF4_HELICASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BCV3.
DR   SWISS-2DPAGE; C5BCV3.
KW   ATP-binding {ECO:0000256|RuleBase:RU362085};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   DNA replication {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740714};
KW   DNA-binding {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000256|SAAS:SAAS00740674};
KW   Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:ACR67559.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU362085,
KW   ECO:0000313|EMBL:ACR67559.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362085};
KW   Primosome {ECO:0000256|RuleBase:RU362085};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485}.
FT   DOMAIN      176    444       SF4 helicase. {ECO:0000259|PROSITE:
FT                                PS51199}.
SQ   SEQUENCE   456 AA;  50449 MW;  791520B9ABDD9709 CRC64;
     MADIHIPHSA EAEQAVLGGL MLDNDRWDEV VLLLAPDDFF VGWHRAIYRA MAELFGASLP
     LDLITLSDRM ENAGLLERVG GFAYLAELSK NTPSAANILA YAGVVAEKSR LRKLQSVGNM
     LVADVQALNA RSSDVLEVAE NQLFCIAEQG MLQVGTETTV NDAMDTLVSR LEAMMALDGL
     TGTPTGFSQL DEMTCGLQPG DLVLLAARPS MGKTALALAT CAAAVRGKPD DYVFVYSMEM
     PEEQLSMRLM SMEGRVELSR LRSASLGDEE WARLSQAMKE IILWNNRLII DDTSYQTPAT
     LRARTRRYVR KYGNPALIMV DYLQLIRSPE QENRTQEIAE ISRSLKAMGK EFGCPVLALS
     QLNRQVEQRA DKRPNNGDLR DSGALEQDAD LIMFIYRDEV YNPGTMTPGV AEIIIGKQRQ
     GPTGTVKVQF DGRYTLFSEY QEGGYDLGYH RKGGRA
//

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