(data stored in ACNUC7421 zone)

SWISSPROT: C5BH63_EDWI9

ID   C5BH63_EDWI9            Unreviewed;       381 AA.
AC   C5BH63;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 56.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase G {ECO:0000256|HAMAP-Rule:MF_01859, ECO:0000256|SAAS:SAAS00696340};
DE            EC=2.1.1.174 {ECO:0000256|HAMAP-Rule:MF_01859};
DE   AltName: Full=23S rRNA m2G1835 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01859};
DE   AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RlmG {ECO:0000256|HAMAP-Rule:MF_01859};
GN   Name=rlmG {ECO:0000256|HAMAP-Rule:MF_01859};
GN   OrderedLocusNames=NT01EI_0512 {ECO:0000313|EMBL:ACR67746.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67746.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the guanine in position 1835
CC       (m2G1835) of 23S rRNA. {ECO:0000256|HAMAP-Rule:MF_01859,
CC       ECO:0000256|SAAS:SAAS00696345}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + guanine(1835) in 23S
CC       rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S
CC       rRNA. {ECO:0000256|HAMAP-Rule:MF_01859,
CC       ECO:0000256|SAAS:SAAS00696336}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01859,
CC       ECO:0000256|SAAS:SAAS00696337}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmG
CC       family. {ECO:0000256|HAMAP-Rule:MF_01859,
CC       ECO:0000256|SAAS:SAAS00696344}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001600; ACR67746.1; -; Genomic_DNA.
DR   RefSeq; WP_015869947.1; NC_012779.2.
DR   ProteinModelPortal; C5BH63; -.
DR   STRING; 634503.NT01EI_0512; -.
DR   EnsemblBacteria; ACR67746; ACR67746; NT01EI_0512.
DR   GeneID; 7961538; -.
DR   KEGG; eic:NT01EI_0512; -.
DR   PATRIC; fig|634503.3.peg.464; -.
DR   eggNOG; ENOG4105D8J; Bacteria.
DR   eggNOG; COG2813; LUCA.
DR   HOGENOM; HOG000246323; -.
DR   KO; K00564; -.
DR   OMA; NLQAWDA; -.
DR   OrthoDB; POG091H05RK; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0052916; F:23S rRNA (guanine(1835)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   HAMAP; MF_01859; 23SrRNA_methyltr_G; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR017237; rRNA_m2G-MeTrfase_RsmD.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   PANTHER; PTHR18895:SF79; PTHR18895:SF79; 1.
DR   Pfam; PF05175; MTS; 1.
DR   PIRSF; PIRSF037565; RRNA_m2G_Mtase_RsmD_prd; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BH63.
DR   SWISS-2DPAGE; C5BH63.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01859,
KW   ECO:0000256|SAAS:SAAS00696338};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01859,
KW   ECO:0000256|SAAS:SAAS00811050, ECO:0000313|EMBL:ACR67746.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01859,
KW   ECO:0000256|SAAS:SAAS00760919};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_01859,
KW   ECO:0000256|SAAS:SAAS00696346};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01859,
KW   ECO:0000256|SAAS:SAAS00811038, ECO:0000313|EMBL:ACR67746.1}.
FT   DOMAIN      205    376       MTS. {ECO:0000259|Pfam:PF05175}.
SQ   SEQUENCE   381 AA;  41600 MW;  1E1C416267CBAD5A CRC64;
     MSQLESSAGC PAITDLTLAR FPHQSDDPSL QAWEAADEYL LQQIDPTQAQ GRPTIIFNDA
     FGALACALHA LRPYSVSDSY VSQLATRHNL QLNDLDGDAV TLLDSLSPLP EAPALVVIKL
     PKMLALLEQQ LHALRAVVAP DTRIIAAAKA RDIHTSTLQL FESILGETHT SLAWKKARLI
     YCQVAERTVI PAPATTVWPL EGTPYTMHNH AGVFSRGSLD IGARFFLQHL PEGLQGEVAD
     LGCGNGVLGL AALSGSPQAR VLFADESYMA VASAHLNVQH NRPQDLARCE FWVGNGLAGR
     EGGTLDAVLC NPPFHQQHSI TDQVAWDMFV AARRCLKRNG VLYIVGNRHL DYYPKLRRLF
     GNCTTLGMNR KFVVLKAVKT V
//

If you have problems or comments...

PBIL Back to PBIL home page