(data stored in ACNUC7421 zone)

SWISSPROT: C5BH74_EDWI9

ID   C5BH74_EDWI9            Unreviewed;       611 AA.
AC   C5BH74;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 67.
DE   RecName: Full=RNA polymerase sigma factor RpoD {ECO:0000256|HAMAP-Rule:MF_00963};
DE   AltName: Full=Sigma-70 {ECO:0000256|HAMAP-Rule:MF_00963};
GN   Name=rpoD {ECO:0000256|HAMAP-Rule:MF_00963};
GN   OrderedLocusNames=NT01EI_0524 {ECO:0000313|EMBL:ACR67757.1};
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503 {ECO:0000313|EMBL:ACR67757.1, ECO:0000313|Proteomes:UP000001485};
RN   [1] {ECO:0000313|Proteomes:UP000001485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146 {ECO:0000313|Proteomes:UP000001485};
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor is the primary sigma factor
CC       during exponential growth. {ECO:0000256|SAAS:SAAS00535554}.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic
CC       core. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003340}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003349}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoD/SigA
CC       subfamily. {ECO:0000256|SAAS:SAAS00535555}.
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DR   EMBL; CP001600; ACR67757.1; -; Genomic_DNA.
DR   RefSeq; WP_015869958.1; NC_012779.2.
DR   STRING; 634503.NT01EI_0524; -.
DR   EnsemblBacteria; ACR67757; ACR67757; NT01EI_0524.
DR   GeneID; 7961549; -.
DR   KEGG; eic:NT01EI_0524; -.
DR   PATRIC; fig|634503.3.peg.474; -.
DR   eggNOG; ENOG4105DG1; Bacteria.
DR   eggNOG; COG0568; LUCA.
DR   HOGENOM; HOG000270272; -.
DR   KO; K03086; -.
DR   OMA; AICSVPY; -.
DR   OrthoDB; POG091H0012; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-HAMAP.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_00963; Sigma70_RpoD_SigA; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR007631; RNA_pol_sigma_70_non-ess.
DR   InterPro; IPR007127; RNA_pol_sigma_70_r1_1.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3_r4.
DR   InterPro; IPR012760; RNA_pol_sigma_RpoD_C.
DR   InterPro; IPR028630; Sigma70_RpoD.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF04546; Sigma70_ner; 1.
DR   Pfam; PF03979; Sigma70_r1_1; 1.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02393; RpoD_Cterm; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5BH74.
DR   SWISS-2DPAGE; C5BH74.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001485};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00051776};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001485};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN      401    414       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      570    596       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    571    590       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00963}.
FT   REGION      377    447       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      456    532       Sigma-70 factor domain-3.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      545    598       Sigma-70 factor domain-4.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   MOTIF       401    404       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00963}.
SQ   SEQUENCE   611 AA;  70169 MW;  56F9B83A4BE7D565 CRC64;
     MEQNPQSQLK LLVTKGKEQG YLTYAEVNDH LPEDIVDSDQ IEDIIQMIND MGIQVMEEAP
     DADDLMLAEN IADEDAAEAA VQVLSSVESE IGRTTDPVRM YMREMGTVEL LTREGEIDIA
     KRIEDGINQV QCSVAEYPEA ITYLLEQYDR VEASEARLSD LITGFVDPNA EEDMAPTATH
     VGSELPEEEL DDDGDENEDE DDDSDDDNSI DPELARQKFV ELRQQYEKTR LAIKAEGRSS
     GKAQEEIQNL SEIFKQFRLV PKQFDYLVSN MREMMDRVRG QERLIMKLCV EQSKMPKKNF
     ITLFTGNETS ITWFDAALAM GKPWGEKLKD MREEVERSLQ KLHQIEEETG LTIEQVKDIN
     RRMSIGEAKA RRAKKEMVEA NLRLVISIAK KYTNRGLQFL DLIQEGNIGL MKAVDKFEYR
     RGYKFSTYAT WWIRQAITRS IADQARTIRI PVHMIETINK LNRISRQMLQ EMGREPTPEE
     LAERMMMPED KIRKVLKIAK EPISMETPIG DDEDSHLGDF IEDTTLELPL DSATSESLRS
     ATRDVLAGLT AREAKVLRMR FGIDMNTDHT LEEVGKQFDV TRERIRQIEA KALRKLRHPS
     RSEVLRSFLD D
//

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