(data stored in ACNUC7421 zone)

SWISSPROT: C6B0G2_RHILS

ID   C6B0G2_RHILS            Unreviewed;        72 AA.
AC   C6B0G2;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   05-JUL-2017, entry version 63.
DE   RecName: Full=Translation initiation factor IF-1 {ECO:0000256|HAMAP-Rule:MF_00075};
GN   Name=infA {ECO:0000256|HAMAP-Rule:MF_00075};
GN   OrderedLocusNames=Rleg_0270 {ECO:0000313|EMBL:ACS54581.1};
OS   Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS54581.1, ECO:0000313|Proteomes:UP000002256};
RN   [1] {ECO:0000313|EMBL:ACS54581.1, ECO:0000313|Proteomes:UP000002256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM1325 {ECO:0000313|EMBL:ACS54581.1,
RC   ECO:0000313|Proteomes:UP000002256};
RX   PubMed=21304718;
RA   Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K.,
RA   Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M.,
RA   Ovchinikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N.,
RA   Melino V., Denton M., Yates R., Howieson J.;
RT   "Complete genome sequence of Rhizobium leguminosarum bv. trifolii
RT   strain WSM1325, an effective microsymbiont of annual Mediterranean
RT   clovers.";
RL   Stand. Genomic Sci. 2:347-356(2010).
CC   -!- FUNCTION: One of the essential components for the initiation of
CC       protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the
CC       30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently
CC       binds. Helps modulate mRNA selection, yielding the 30S pre-
CC       initiation complex (PIC). Upon addition of the 50S ribosomal
CC       subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S
CC       translation initation complex. {ECO:0000256|HAMAP-Rule:MF_00075,
CC       ECO:0000256|SAAS:SAAS00571772}.
CC   -!- SUBUNIT: Component of the 30S ribosomal translation pre-initiation
CC       complex which assembles on the 30S ribosome in the order IF-2 and
CC       IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can
CC       occur at any time during PIC assembly. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00385842}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075}.
CC   -!- SIMILARITY: Belongs to the IF-1 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00571750}.
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DR   EMBL; CP001622; ACS54581.1; -; Genomic_DNA.
DR   RefSeq; WP_003545338.1; NC_012850.1.
DR   ProteinModelPortal; C6B0G2; -.
DR   SMR; C6B0G2; -.
DR   EnsemblBacteria; ACS54581; ACS54581; Rleg_0270.
DR   GeneID; 32046728; -.
DR   KEGG; rlg:Rleg_0270; -.
DR   HOGENOM; HOG000221323; -.
DR   KO; K02518; -.
DR   OMA; AHVSGKM; -.
DR   OrthoDB; POG091H019C; -.
DR   Proteomes; UP000002256; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   CDD; cd04451; S1_IF1; 1.
DR   HAMAP; MF_00075; IF_1; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR004368; TIF_IF1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00008; infA; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C6B0G2.
DR   SWISS-2DPAGE; C6B0G2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002256};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00090884,
KW   ECO:0000313|EMBL:ACS54581.1};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00090890};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571736};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571793}.
FT   DOMAIN        1     72       S1-like. {ECO:0000259|PROSITE:PS50832}.
SQ   SEQUENCE   72 AA;  8382 MW;  80543208323332D6 CRC64;
     MPKEEVLEFP GIVTELLPNA TFRVKLENEH EIIAHTAGRM RKNRIRVLAG DKVLVEMTPY
     DLTKGRITYR FK
//

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