(data stored in ACNUC7421 zone)

SWISSPROT: C6B2H2_RHILS

ID   C6B2H2_RHILS            Unreviewed;       245 AA.
AC   C6B2H2;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   07-JUN-2017, entry version 46.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase E {ECO:0000256|PIRNR:PIRNR015601};
DE            EC=2.1.1.193 {ECO:0000256|PIRNR:PIRNR015601};
GN   OrderedLocusNames=Rleg_0486 {ECO:0000313|EMBL:ACS54792.1};
OS   Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS54792.1, ECO:0000313|Proteomes:UP000002256};
RN   [1] {ECO:0000313|EMBL:ACS54792.1, ECO:0000313|Proteomes:UP000002256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM1325 {ECO:0000313|EMBL:ACS54792.1,
RC   ECO:0000313|Proteomes:UP000002256};
RX   PubMed=21304718;
RA   Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K.,
RA   Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M.,
RA   Ovchinikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N.,
RA   Melino V., Denton M., Yates R., Howieson J.;
RT   "Complete genome sequence of Rhizobium leguminosarum bv. trifolii
RT   strain WSM1325, an effective microsymbiont of annual Mediterranean
RT   clovers.";
RL   Stand. Genomic Sci. 2:347-356(2010).
CC   -!- FUNCTION: Specifically methylates the N3 position of the uracil
CC       ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully
CC       assembled 30S ribosomal subunit. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + uracil(1498) in 16S
CC       rRNA = S-adenosyl-L-homocysteine + N(3)-methyluracil(1498) in 16S
CC       rRNA. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase RsmE family.
CC       {ECO:0000256|PIRNR:PIRNR015601}.
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DR   EMBL; CP001622; ACS54792.1; -; Genomic_DNA.
DR   RefSeq; WP_012756178.1; NC_012850.1.
DR   ProteinModelPortal; C6B2H2; -.
DR   EnsemblBacteria; ACS54792; ACS54792; Rleg_0486.
DR   KEGG; rlg:Rleg_0486; -.
DR   HOGENOM; HOG000015266; -.
DR   KO; K09761; -.
DR   OMA; ERMEFTI; -.
DR   OrthoDB; POG091H02MI; -.
DR   BioCyc; RLEG395491:GHX2-488-MONOMER; -.
DR   Proteomes; UP000002256; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR015947; PUA-like_domain.
DR   InterPro; IPR006700; rRNA_ssu_MeTrfase-E.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR30027; PTHR30027; 1.
DR   Pfam; PF04452; Methyltrans_RNA; 1.
DR   PIRSF; PIRSF015601; MTase_slr0722; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00046; TIGR00046; 1.
PE   3: Inferred from homology;
DR   PRODOM; C6B2H2.
DR   SWISS-2DPAGE; C6B2H2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002256};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR015601};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR015601};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR015601};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR015601};
KW   Transferase {ECO:0000256|PIRNR:PIRNR015601}.
SQ   SEQUENCE   245 AA;  27119 MW;  E5285D111117F591 CRC64;
     MRANFRMQRL FVDAPLTRGA GVEANADQFN YLANVLRMED GGEILLFNGR DGEWKATLTF
     PTRKRILLTA TEETRPQPQP CDLHYLFAPL KVGRMDYLVQ KAVEMGAGLL QPVMTQHVQG
     KVTNLDKLRA NVIEAAEQCG ILGIPDVAEP VRLLDLLDRW PSERRIIYCD EGDAGQNPLP
     VLSAIRERHL ALLVGPEGGF SEEERARLRS LDFVTAIPLG PRILRADTAA VAALAVVQAA
     IGDWN
//

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