(data stored in ACNUC7421 zone)

SWISSPROT: C6WCH2_ACTMD

ID   C6WCH2_ACTMD            Unreviewed;       448 AA.
AC   C6WCH2;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   08-MAY-2019, entry version 59.
DE   SubName: Full=Ferredoxin--NADP(+) reductase {ECO:0000313|EMBL:ACU33993.1};
DE            EC=1.18.1.2 {ECO:0000313|EMBL:ACU33993.1};
GN   OrderedLocusNames=Amir_0019 {ECO:0000313|EMBL:ACU33993.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU
OS   3971).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU33993.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU33993.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971
RC   {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D.,
RA   Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Hauser L., Chang Y.J.,
RA   Jeffries C.C., Brettin T., Detter J.C., Han C., Chain P.,
RA   Tindall B.J., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000362-1};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001630; ACU33993.1; -; Genomic_DNA.
DR   RefSeq; WP_012782656.1; NC_013093.1.
DR   STRING; 446462.Amir_0019; -.
DR   EnsemblBacteria; ACU33993; ACU33993; Amir_0019.
DR   KEGG; ami:Amir_0019; -.
DR   eggNOG; ENOG4105EQH; Bacteria.
DR   eggNOG; COG0493; LUCA.
DR   HOGENOM; HOG000249250; -.
DR   KO; K00528; -.
DR   OMA; RFNFIGN; -.
DR   OrthoDB; 671513at2; -.
DR   BioCyc; AMIR446462:G1GEY-20-MONOMER; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR021163; Ferredox_Rdtase_adrenod.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PIRSF; PIRSF000362; FNR; 1.
PE   4: Predicted;
DR   PRODOM; C6WCH2.
DR   SWISS-2DPAGE; C6WCH2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002213};
KW   FAD {ECO:0000256|PIRSR:PIRSR000362-1};
KW   Flavoprotein {ECO:0000256|PIRSR:PIRSR000362-1};
KW   NADP {ECO:0000256|PIRSR:PIRSR000362-2};
KW   Oxidoreductase {ECO:0000313|EMBL:ACU33993.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT   DOMAIN        6    178       Pyr_redox_2. {ECO:0000259|Pfam:PF07992}.
FT   NP_BIND     194    195       NADP. {ECO:0000256|PIRSR:PIRSR000362-2}.
FT   NP_BIND     364    366       FAD. {ECO:0000256|PIRSR:PIRSR000362-1}.
FT   BINDING      15     15       FAD; via amide nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR000362-1}.
FT   BINDING      36     36       FAD. {ECO:0000256|PIRSR:PIRSR000362-1}.
FT   BINDING      44     44       FAD; via amide nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR000362-1}.
FT   BINDING     206    206       NADP. {ECO:0000256|PIRSR:PIRSR000362-2}.
FT   BINDING     357    357       FAD; via amide nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR000362-1}.
FT   BINDING     364    364       NADP; via amide nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR000362-2}.
SQ   SEQUENCE   448 AA;  48844 MW;  55A2377962F98692 CRC64;
     MSRSLRVAVV GAGPAGIYAA DILTKSDAEV SIDLFERMPA PYGLIRYGVA PDHPRIKGIV
     NALQKVLDRP EIRFFGNVEY GVDVKLEDLR QHYDAVIFST GAEKDRAMDV PGIELDGSYG
     AADFVSWYDG HPDVPRTWPL TASQVAVLGV GNVALDVARV LAKTADELLT TEIPDNVYEG
     LKSSPVTDVH VFGRRGPAQA KFTPLELREL DHSPNVEVIV HPEGIDFDEG SMASIRSSKQ
     VEMVVKTLQE WALRDVGDRP RRLHLHFLEA PVEVTGEDGK VVGLRTERME LAGDGNVKGT
     GEFTDWPVQA VYRAVGYLST SLVDLPFDTA SGTVPHAGGR VVDLDEQPLP GVYVTGWIKR
     GPVGLIGHTK GDALETVTNL LADADALPAC QFPEPDAIVR FLEQRAVPFT TVEGWLKLDA
     HEKALGAERG RERVKVVDRE TMTSVSRS
//

If you have problems or comments...

PBIL Back to PBIL home page