(data stored in ACNUC7421 zone)

SWISSPROT: C6WGH0_ACTMD

ID   C6WGH0_ACTMD            Unreviewed;       158 AA.
AC   C6WGH0;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   07-JUN-2017, entry version 46.
DE   SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase {ECO:0000313|EMBL:ACU34286.1};
DE            EC=2.7.6.3 {ECO:0000313|EMBL:ACU34286.1};
GN   OrderedLocusNames=Amir_0317 {ECO:0000313|EMBL:ACU34286.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU
OS   3971).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU34286.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU34286.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971
RC   {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D.,
RA   Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Hauser L., Chang Y.J.,
RA   Jeffries C.C., Brettin T., Detter J.C., Han C., Chain P.,
RA   Tindall B.J., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
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DR   EMBL; CP001630; ACU34286.1; -; Genomic_DNA.
DR   RefSeq; WP_012782949.1; NC_013093.1.
DR   STRING; 446462.Amir_0317; -.
DR   EnsemblBacteria; ACU34286; ACU34286; Amir_0317.
DR   KEGG; ami:Amir_0317; -.
DR   eggNOG; ENOG4105K8U; Bacteria.
DR   eggNOG; COG0801; LUCA.
DR   HOGENOM; HOG000217741; -.
DR   KO; K00950; -.
DR   OMA; KDERWGP; -.
DR   OrthoDB; POG091H000M; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   CDD; cd00483; HPPK; 1.
DR   Gene3D; 3.30.70.560; -; 1.
DR   InterPro; IPR000550; Hppk.
DR   Pfam; PF01288; HPPK; 1.
DR   SUPFAM; SSF55083; SSF55083; 1.
DR   TIGRFAMs; TIGR01498; folK; 1.
DR   PROSITE; PS00794; HPPK; 1.
PE   4: Predicted;
DR   PRODOM; C6WGH0.
DR   SWISS-2DPAGE; C6WGH0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002213};
KW   Kinase {ECO:0000313|EMBL:ACU34286.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW   Transferase {ECO:0000313|EMBL:ACU34286.1}.
FT   DOMAIN       84     95       HPPK. {ECO:0000259|PROSITE:PS00794}.
SQ   SEQUENCE   158 AA;  17381 MW;  92811357A67353BB CRC64;
     MSRAVLSLGS NLGDRLAHLR SAVDGFRPWL LAASPVYETA PWGVTDQDDF LNAVLLVEGD
     LDEWGWLRRG QELERAAGRV RERRWGPRTL DVDVVAVDDV RSEDPELLLP HPGAHERATV
     LAPWLDVDPD AVLPGHGRVA DLLSGVDLSG VRRLEVAL
//

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