(data stored in ACNUC7421 zone)

SWISSPROT: C6WI24_ACTMD

ID   C6WI24_ACTMD            Unreviewed;       100 AA.
AC   C6WI24;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=Urease subunit gamma {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850};
DE            EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850};
DE   AltName: Full=Urea amidohydrolase subunit gamma {ECO:0000256|HAMAP-Rule:MF_00739};
GN   Name=ureA {ECO:0000256|HAMAP-Rule:MF_00739};
GN   OrderedLocusNames=Amir_0508 {ECO:0000313|EMBL:ACU34475.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU
OS   3971).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU34475.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU34475.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971
RC   {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D.,
RA   Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Hauser L., Chang Y.J.,
RA   Jeffries C.C., Brettin T., Detter J.C., Han C., Chain P.,
RA   Tindall B.J., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
CC   -!- CATALYTIC ACTIVITY: Urea + H(2)O = CO(2) + 2 NH(3).
CC       {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850,
CC       ECO:0000256|SAAS:SAAS00655169}.
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_00739, ECO:0000256|SAAS:SAAS00655187}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC
CC       (alpha) subunits. Three heterotrimers associate to form the active
CC       enzyme. {ECO:0000256|HAMAP-Rule:MF_00739,
CC       ECO:0000256|SAAS:SAAS00779034}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00739,
CC       ECO:0000256|RuleBase:RU003850, ECO:0000256|SAAS:SAAS00750640}.
CC   -!- SIMILARITY: Belongs to the urease gamma subunit family.
CC       {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850,
CC       ECO:0000256|SAAS:SAAS00779048}.
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DR   EMBL; CP001630; ACU34475.1; -; Genomic_DNA.
DR   RefSeq; WP_012783138.1; NC_013093.1.
DR   STRING; 446462.Amir_0508; -.
DR   EnsemblBacteria; ACU34475; ACU34475; Amir_0508.
DR   KEGG; ami:Amir_0508; -.
DR   eggNOG; ENOG4108YZ9; Bacteria.
DR   eggNOG; COG0831; LUCA.
DR   HOGENOM; HOG000075053; -.
DR   KO; K01430; -.
DR   OMA; ELMSYGT; -.
DR   OrthoDB; POG091H09TI; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_00739; Urease_gamma; 1.
DR   InterPro; IPR012010; Urease_gamma.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001223; Urease_gamma; 1.
DR   ProDom; PD002319; Urease_gamma_reg; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   3: Inferred from homology;
DR   PRODOM; C6WI24.
DR   SWISS-2DPAGE; C6WI24.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002213};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00739,
KW   ECO:0000256|SAAS:SAAS00750644};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00739,
KW   ECO:0000256|RuleBase:RU003850, ECO:0000256|SAAS:SAAS00655182,
KW   ECO:0000313|EMBL:ACU34475.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213}.
SQ   SEQUENCE   100 AA;  10977 MW;  89985FC5EEDD3C3A CRC64;
     MHLTPHERDK LLVHVAADVA RRRLERGVAL NHPESVALIT SHVLEGARDG RTVGELMASG
     RHVLTREQVM DGVPEMIDSV QVEATFPDGT KLVTVHDPIS
//

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