(data stored in ACNUC7421 zone)

SWISSPROT: C7PVJ8_CATAD

ID   C7PVJ8_CATAD            Unreviewed;       509 AA.
AC   C7PVJ8;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   07-JUN-2017, entry version 48.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACU69354.1};
GN   OrderedLocusNames=Caci_0402 {ECO:0000313|EMBL:ACU69354.1};
OS   Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC
OS   102108 / JCM 14897).
OC   Bacteria; Actinobacteria; Catenulisporales; Catenulisporaceae;
OC   Catenulispora.
OX   NCBI_TaxID=479433 {ECO:0000313|EMBL:ACU69354.1, ECO:0000313|Proteomes:UP000000851};
RN   [1] {ECO:0000313|EMBL:ACU69354.1, ECO:0000313|Proteomes:UP000000851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897
RC   {ECO:0000313|Proteomes:UP000000851};
RX   PubMed=21304647;
RA   Copeland A., Lapidus A., Glavina Del Rio T., Nolan M., Lucas S.,
RA   Chen F., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA   Mikhailova N., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chertkov O., Brettin T., Detter J.C., Han C., Ali Z.,
RA   Tindall B.J., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Catenulispora acidiphila type strain (ID
RT   139908).";
RL   Stand. Genomic Sci. 1:119-125(2009).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001700; ACU69354.1; -; Genomic_DNA.
DR   RefSeq; WP_012784649.1; NC_013131.1.
DR   STRING; 479433.Caci_0402; -.
DR   EnsemblBacteria; ACU69354; ACU69354; Caci_0402.
DR   KEGG; cai:Caci_0402; -.
DR   eggNOG; ENOG4105EDF; Bacteria.
DR   eggNOG; ENOG410XQZX; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; LMCLGIF; -.
DR   OrthoDB; POG091H0CG8; -.
DR   Proteomes; UP000000851; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; Drug-R_transpt_efflux_EmrB.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 2.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; C7PVJ8.
DR   SWISS-2DPAGE; C7PVJ8.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000851};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000851};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     33     57       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     72     89       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    101    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    159    182       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    188    210       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    222    242       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    254    273       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    294    315       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    321    344       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    356    375       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    381    401       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    429    452       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    472    491       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    495       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   509 AA;  52635 MW;  857DB127D4217AD0 CRC64;
     MADLRTTGAE AQTADAAPAD HTDHTDPHHA RRWFILGIIG LAQLMIVLDV TIVNIALPDA
     QKALGFSNGD RQWIVTAYSL AFGSLLLLFG RVSDVIGRRA MFLIGLVGFA AASALGGAAP
     NFEILVLARA LQGVAGAMLA PAALSLLSTT FTEAKERATA FAVFGGIAGS GAAIGMLLGG
     VLTEFLNWRW TLFVNVGISV IAIAGAAVLI PRHARSADRP SLDIPGTVLV SAGLFGIVYG
     FANAESHPWS APGTWGFLVA GLVLLGAFTF WQTRTKHPLL PLRVILERNR GGSYLAMFLT
     GIGMFGVFLF LNYYLQEILR YSPVMTGVAF LPMVAALMIT ATISTTQLYP RVGAKILVFA
     GMLLAGAGMV WLTGISLTSS YAANILGPTV VVGIGMGAIF APAMNAATSG VEAGDAGVAS
     AMVNTAQQIG GSIGTALLNS LAASALTSYL VGKNATNPVV QANAAIHSYV VAFWWAAAIF
     GVGAIICGLI LKSGKPDPAD PDAAPAIHA
//

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