(data stored in ACNUC7421 zone)

SWISSPROT: D1CDD0_THET1

ID   D1CDD0_THET1            Unreviewed;       306 AA.
AC   D1CDD0;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   08-MAY-2019, entry version 56.
DE   RecName: Full=Malonyl CoA-acyl carrier protein transacylase {ECO:0000256|PIRNR:PIRNR000446};
DE            EC=2.3.1.39 {ECO:0000256|PIRNR:PIRNR000446};
GN   OrderedLocusNames=Tter_0013 {ECO:0000313|EMBL:ACZ40936.1};
OS   Thermobaculum terrenum (strain ATCC BAA-798 / YNP1).
OC   Bacteria; Thermobaculum.
OX   NCBI_TaxID=525904 {ECO:0000313|EMBL:ACZ40936.1, ECO:0000313|Proteomes:UP000000323};
RN   [1] {ECO:0000313|EMBL:ACZ40936.1, ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   PubMed=21304745;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Del Rio T.G., Nolan M.,
RA   Tice H., Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA   Mavromatis K., Ovchinnikova G., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Lu M., Brettin T.,
RA   Detter J.C., Goker M., Tindall B.J., Beck B., McDermott T.R.,
RA   Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Cheng J.F.;
RT   "Complete genome sequence of 'Thermobaculum terrenum' type strain
RT   (YNP1).";
RL   Stand. Genomic Sci. 3:153-162(2010).
RN   [2] {ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   DOI=10.4056/sigs.1153107;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Glavina Del Rio T.,
RA   Nolan M., Tice H., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Lu M.,
RA   Brettin T., Detter J., Goker M., Tindall B., Beck B., McDermott T.,
RA   Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA   Kyrpides N., Klenk H., Cheng J.;
RT   "Complete genome sequence of Thermobaculum terrenum type strain
RT   (YNP1T).";
RL   Stand. Genomic Sci. 3:153-162(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP];
CC         Xref=Rhea:RHEA:41792, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57384, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:78449; EC=2.3.1.39;
CC         Evidence={ECO:0000256|PIRNR:PIRNR000446};
CC   -!- SIMILARITY: Belongs to the fabD family.
CC       {ECO:0000256|PIRNR:PIRNR000446}.
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DR   EMBL; CP001825; ACZ40936.1; -; Genomic_DNA.
DR   RefSeq; WP_012873971.1; NC_013525.1.
DR   STRING; 525904.Tter_0013; -.
DR   EnsemblBacteria; ACZ40936; ACZ40936; Tter_0013.
DR   KEGG; ttr:Tter_0013; -.
DR   eggNOG; ENOG4105CJF; Bacteria.
DR   eggNOG; COG0331; LUCA.
DR   HOGENOM; HOG000036504; -.
DR   KO; K00645; -.
DR   OMA; AANYNCP; -.
DR   OrthoDB; 1123553at2; -.
DR   BioCyc; TTER525904:G1GGS-13-MONOMER; -.
DR   Proteomes; UP000000323; Chromosome 1.
DR   GO; GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.366.10; -; 1.
DR   InterPro; IPR001227; Ac_transferase_dom_sf.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR024925; Malonyl_CoA-ACP_transAc.
DR   InterPro; IPR004410; Malonyl_CoA-ACP_transAc_FabD.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   PIRSF; PIRSF000446; Mct; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   SUPFAM; SSF55048; SSF55048; 1.
DR   TIGRFAMs; TIGR00128; fabD; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1CDD0.
DR   SWISS-2DPAGE; D1CDD0.
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000446};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000323};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000323};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000446}.
FT   DOMAIN        9    304       PKS_AT. {ECO:0000259|SMART:SM00827}.
FT   ACT_SITE     99     99       {ECO:0000256|PIRSR:PIRSR000446-1}.
FT   ACT_SITE    208    208       {ECO:0000256|PIRSR:PIRSR000446-1}.
SQ   SEQUENCE   306 AA;  33060 MW;  65FB43B5605F5B21 CRC64;
     MSSRRIALVF PGQGSQYVGM GKALHDASEA AREVFKRADE ILGFRLSHLC FSGPEEDLQD
     TINAQPAIFT VSLATLAAIK EKLHEAGVKL NPSFVAGHSL GEYTALVAAN VIDFEDGLRL
     VRERGRLMKE EGEKIPGGMA AVIGLDEEVI QRACEEASSE GIVGIANSNS PGQIVISGEL
     KALHRAMELL QQQGAKKVIK LPISIASHSP VMQRAAAQFA EIVSHMKLRD PQIPIVANVT
     GQILTNVEDI RRELSHHITG PVQWTKSIRE MLSHGTNGFI ELGPKRVLTG LIQRISPGVD
     TISTDS
//

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