(data stored in ACNUC7421 zone)

SWISSPROT: D1CE61_THET1

ID   D1CE61_THET1            Unreviewed;       114 AA.
AC   D1CE61;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   16-JAN-2019, entry version 50.
DE   RecName: Full=Adenosylmethionine decarboxylase {ECO:0000256|SAAS:SAAS00990818};
DE            EC=4.1.1.50 {ECO:0000256|SAAS:SAAS00990818};
GN   OrderedLocusNames=Tter_0295 {ECO:0000313|EMBL:ACZ41217.1};
OS   Thermobaculum terrenum (strain ATCC BAA-798 / YNP1).
OC   Bacteria; Thermobaculum.
OX   NCBI_TaxID=525904 {ECO:0000313|EMBL:ACZ41217.1, ECO:0000313|Proteomes:UP000000323};
RN   [1] {ECO:0000313|EMBL:ACZ41217.1, ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   PubMed=21304745;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Del Rio T.G., Nolan M.,
RA   Tice H., Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA   Mavromatis K., Ovchinnikova G., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Lu M., Brettin T.,
RA   Detter J.C., Goker M., Tindall B.J., Beck B., McDermott T.R.,
RA   Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Cheng J.F.;
RT   "Complete genome sequence of 'Thermobaculum terrenum' type strain
RT   (YNP1).";
RL   Stand. Genomic Sci. 3:153-162(2010).
RN   [2] {ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   DOI=10.4056/sigs.1153107;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Glavina Del Rio T.,
RA   Nolan M., Tice H., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Lu M.,
RA   Brettin T., Detter J., Goker M., Tindall B., Beck B., McDermott T.,
RA   Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA   Kyrpides N., Klenk H., Cheng J.;
RT   "Complete genome sequence of Thermobaculum terrenum type strain
RT   (YNP1T).";
RL   Stand. Genomic Sci. 3:153-162(2010).
CC   -!- FUNCTION: Catalyzes the decarboxylation of S-adenosylmethionine to
CC       S-adenosylmethioninamine (dcAdoMet), the propylamine donor
CC       required for the synthesis of the polyamines spermine and
CC       spermidine from the diamine putrescine.
CC       {ECO:0000256|SAAS:SAAS00990819}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-
CC         (methylsulfanyl)propylamine; Xref=Rhea:RHEA:15981,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57443,
CC         ChEBI:CHEBI:59789; EC=4.1.1.50;
CC         Evidence={ECO:0000256|SAAS:SAAS01120362};
CC   -!- PATHWAY: Amine and polyamine biosynthesis; S-
CC       adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from
CC       S-adenosyl-L-methionine: step 1/1.
CC       {ECO:0000256|SAAS:SAAS00990826}.
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DR   EMBL; CP001825; ACZ41217.1; -; Genomic_DNA.
DR   RefSeq; WP_012874252.1; NC_013525.1.
DR   STRING; 525904.Tter_0295; -.
DR   EnsemblBacteria; ACZ41217; ACZ41217; Tter_0295.
DR   KEGG; ttr:Tter_0295; -.
DR   eggNOG; ENOG4105X3E; Bacteria.
DR   eggNOG; COG1586; LUCA.
DR   HOGENOM; HOG000216579; -.
DR   KO; K01611; -.
DR   OrthoDB; 1613081at2; -.
DR   BioCyc; TTER525904:G1GGS-298-MONOMER; -.
DR   UniPathway; UPA00331; UER00451.
DR   Proteomes; UP000000323; Chromosome 1.
DR   GO; GO:0004014; F:adenosylmethionine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006557; P:S-adenosylmethioninamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR003826; AdoMetDC_fam_prok.
DR   InterPro; IPR016067; S-AdoMet_deCO2ase_core.
DR   InterPro; IPR017716; S-AdoMet_deCOase_pro-enz.
DR   PANTHER; PTHR33866; PTHR33866; 1.
DR   Pfam; PF02675; AdoMet_dc; 1.
DR   SUPFAM; SSF56276; SSF56276; 1.
DR   TIGRFAMs; TIGR03330; SAM_DCase_Bsu; 1.
PE   4: Predicted;
DR   PRODOM; D1CE61.
DR   SWISS-2DPAGE; D1CE61.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000323};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000323};
KW   S-adenosyl-L-methionine {ECO:0000256|SAAS:SAAS00990835};
KW   Spermidine biosynthesis {ECO:0000256|SAAS:SAAS00990844}.
SQ   SEQUENCE   114 AA;  13115 MW;  9F1ED17B35FBF8F9 CRC64;
     MSFRHILYDL WVEDPSILER TKPLEQIMLE AARCSGATIL HSYFHQFDPH GVSGVVLIAQ
     SHLSIHTWSE EKYAAIDVFT YQGMNPELAI SYIREKLRPT RERITDLSRG GTLL
//

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