(data stored in ACNUC7421 zone)

SWISSPROT: D3F4W1_CONWI

ID   D3F4W1_CONWI            Unreviewed;       662 AA.
AC   D3F4W1;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   07-JUN-2017, entry version 52.
DE   RecName: Full=Transketolase {ECO:0000256|RuleBase:RU004996};
DE            EC=2.2.1.1 {ECO:0000256|RuleBase:RU004996};
GN   OrderedLocusNames=Cwoe_0103 {ECO:0000313|EMBL:ADB48539.1};
OS   Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 /
OS   ID131577).
OC   Bacteria; Actinobacteria; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB48539.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K.,
RA   Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the transfer of a two-carbon ketol group from
CC       a ketose donor to an aldose acceptor, via a covalent intermediate
CC       with the cofactor thiamine pyrophosphate.
CC       {ECO:0000256|RuleBase:RU004996}.
CC   -!- CATALYTIC ACTIVITY: Sedoheptulose 7-phosphate + D-glyceraldehyde
CC       3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
CC       {ECO:0000256|RuleBase:RU004996}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU004996}.
CC   -!- SIMILARITY: Belongs to the transketolase family.
CC       {ECO:0000256|RuleBase:RU004996, ECO:0000256|SAAS:SAAS00651207}.
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DR   EMBL; CP001854; ADB48539.1; -; Genomic_DNA.
DR   RefSeq; WP_012931592.1; NC_013739.1.
DR   ProteinModelPortal; D3F4W1; -.
DR   STRING; 469383.Cwoe_0103; -.
DR   EnsemblBacteria; ADB48539; ADB48539; Cwoe_0103.
DR   KEGG; cwo:Cwoe_0103; -.
DR   eggNOG; ENOG4105CV1; Bacteria.
DR   eggNOG; COG0021; LUCA.
DR   HOGENOM; HOG000225953; -.
DR   KO; K00615; -.
DR   OMA; FADYMRG; -.
DR   OrthoDB; POG091H02B4; -.
DR   BioCyc; CWOE469383:GH82-103-MONOMER; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR005478; Transketolase_bac-like.
DR   InterPro; IPR020826; Transketolase_BS.
DR   InterPro; IPR033248; Transketolase_C.
DR   InterPro; IPR033247; Transketolase_fam.
DR   InterPro; IPR005474; Transketolase_N.
DR   PANTHER; PTHR43522; PTHR43522; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   Pfam; PF00456; Transketolase_N; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   SUPFAM; SSF52922; SSF52922; 1.
DR   TIGRFAMs; TIGR00232; tktlase_bact; 1.
DR   PROSITE; PS00801; TRANSKETOLASE_1; 1.
DR   PROSITE; PS00802; TRANSKETOLASE_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3F4W1.
DR   SWISS-2DPAGE; D3F4W1.
KW   Calcium {ECO:0000256|RuleBase:RU004996};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008229};
KW   Magnesium {ECO:0000256|RuleBase:RU004996,
KW   ECO:0000256|SAAS:SAAS00651250};
KW   Metal-binding {ECO:0000256|RuleBase:RU004996,
KW   ECO:0000256|SAAS:SAAS00651225};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229};
KW   Thiamine pyrophosphate {ECO:0000256|RuleBase:RU004996,
KW   ECO:0000256|SAAS:SAAS00651235};
KW   Transferase {ECO:0000256|RuleBase:RU004996,
KW   ECO:0000256|SAAS:SAAS00651241}.
FT   DOMAIN       17     37       TRANSKETOLASE_1. {ECO:0000259|PROSITE:
FT                                PS00801}.
SQ   SEQUENCE   662 AA;  71332 MW;  EB67B576E4EB1801 CRC64;
     MATTAQSTEQ LAVDTIRTLA MDAVQNTGNG HPGMPMGMAP VGYLLFSEVM RHNPTDPHWP
     DRDRFVLSAG HGSMLLYACL HLSGYDVTMD DIKHFRQWGS RTPGHPEVHH TPGVETTTGP
     LGQGFANAVG MAIAERFLRE HFGAEVQDHR IYGICSDGDL MEGVSAEAAS LAGHLGLGHL
     IFLYDHNHIS IDGHTSLTFD TEDVNERFDA YGWHTQDVDD VTDLDALRAA IAAAQQETGR
     PSLIRVRSKI GYPAPNKQDT PGAHGAALGE DEVRATKEVM GWDPDQHFVV PDGVYDLFSA
     VEDGKRHQAA WEERYQSWRA ADGERATRWD LAWAGKPLPG LDAALPQFDP ADKPSLATRS
     AGGTTLQTIA RFLPTMVGGS ADLNESVKTG IAADGPYSRE QATRNVYWGI REHAMGAAVN
     GLALHGGIVK PYGGTFLQFA DYMRPALRLS ALMHLPVVWV YTHDSVALGE DGPTHQPVEH
     LAALRAIPGL TLIRPSDANE TAEAWRVAVE DVDGPVVLVL TRQNVPTLER PPYAPAKGID
     KGAYVLADAD DAVATIVGTG SEVSVALGAR DLLAAEGVAA RVVAMPSWEL FEAQDQAYRD
     EVLPPGQPKV AVEAGIAMGW ERWVDATVSI ERFGASAAGE KILEEYGITA AAVAERVRSL
     LT
//

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