(data stored in ACNUC7421 zone)

SWISSPROT: D3F513_CONWI

ID   D3F513_CONWI            Unreviewed;       487 AA.
AC   D3F513;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   07-JUN-2017, entry version 39.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ADB48591.1};
GN   OrderedLocusNames=Cwoe_0155 {ECO:0000313|EMBL:ADB48591.1};
OS   Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 /
OS   ID131577).
OC   Bacteria; Actinobacteria; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB48591.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K.,
RA   Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001854; ADB48591.1; -; Genomic_DNA.
DR   RefSeq; WP_012931644.1; NC_013739.1.
DR   STRING; 469383.Cwoe_0155; -.
DR   EnsemblBacteria; ADB48591; ADB48591; Cwoe_0155.
DR   KEGG; cwo:Cwoe_0155; -.
DR   eggNOG; ENOG4105DNW; Bacteria.
DR   eggNOG; ENOG410XQ4D; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; SHWHYST; -.
DR   OrthoDB; POG091H0MDR; -.
DR   BioCyc; CWOE469383:GH82-155-MONOMER; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; Drug-R_transpt_efflux_EmrB.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; SSF103473; 2.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3F513.
DR   SWISS-2DPAGE; D3F513.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008229};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     26     48       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     93    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    144       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    151    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    180    201       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    213    231       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    237    259       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    280    305       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    311    334       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    346    367       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    373    398       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    419    439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    445    464       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    468       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   487 AA;  48380 MW;  3DCFC218D8FC7E2D CRC64;
     MSGPAAPAAT PLGSESPPAA PRPGRAIAVA SAATFVAFLD VTVVNVALPD LQRDFAGASL
     VTLSWVVAIY GVLFAALLTP AGRLADVIGR KTVFLAGFAG FTVTSAISAV APSVGLLIAA
     RALQGASAAF MIPAALGIVL AVSAPEKRAA AVGLWGATTS VAAAAGPALG GLLIDAFDWR
     AVFLINVPIG LVVLWAGWRV LPSIGRGAQQ LPDLIGSALL AAGFALVLVA LTETAEWGWV
     DGRTAACLVA GVALLAVVLR RTRSHPAPAI ELALLRNRAF AVASAGAALY GVALFAWMLA
     CVLFVTSVWG YSIIEAGLAV TPGAFSSAVA AVFAGRVVDR HGPRGVVAGA SLLFAAAGVW
     CVLGISAEPR FLTFWLPLGI VGGAGMGAVT VGLTGAAARA LPPAQFASGT GLAMTARQLG
     GALGVAALAT ILESAGVGVA GFRAVFAMCT VAALLTALSA LWLARPAPTA APAAAPLEPS
     KTAEVVA
//

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