(data stored in SCRATCH3701 zone)

SWISSPROT: D5E926_METMS

ID   D5E926_METMS            Unreviewed;       538 AA.
AC   D5E926;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 44.
DE   SubName: Full=IMP cyclohydrolase phosphoribosylaminoimidazolecarboxamide formyltransferase {ECO:0000313|EMBL:ADE35677.1};
DE            EC=2.1.2.3 {ECO:0000313|EMBL:ADE35677.1};
DE            EC=3.5.4.10 {ECO:0000313|EMBL:ADE35677.1};
GN   OrderedLocusNames=Mmah_0142 {ECO:0000313|EMBL:ADE35677.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35677.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE35677.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001994; ADE35677.1; -; Genomic_DNA.
DR   RefSeq; WP_013036620.1; NC_014002.1.
DR   EnsemblBacteria; ADE35677; ADE35677; Mmah_0142.
DR   GeneID; 8982273; -.
DR   KEGG; mmh:Mmah_0142; -.
DR   eggNOG; arCOG02824; Archaea.
DR   eggNOG; COG0138; LUCA.
DR   HOGENOM; HOG000230372; -.
DR   KO; K00602; -.
DR   OMA; WRVAKFV; -.
DR   OrthoDB; 37310at2157; -.
DR   BioCyc; MMAH547558:G1GHT-141-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0003937; F:IMP cyclohydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004643; F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.140.20; -; 2.
DR   Gene3D; 3.40.50.1380; -; 1.
DR   HAMAP; MF_00139; PurH; 1.
DR   InterPro; IPR024051; AICAR_Tfase_dup_dom_sf.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR011607; MGS-like_dom.
DR   InterPro; IPR036914; MGS-like_dom_sf.
DR   InterPro; IPR002695; PurH-like.
DR   PANTHER; PTHR11692; PTHR11692; 1.
DR   Pfam; PF01808; AICARFT_IMPCHas; 1.
DR   Pfam; PF02142; MGS; 1.
DR   PIRSF; PIRSF000414; AICARFT_IMPCHas; 1.
DR   SMART; SM00798; AICARFT_IMPCHas; 1.
DR   SMART; SM00851; MGS; 1.
DR   SUPFAM; SSF52335; SSF52335; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00355; purH; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5E926.
DR   SWISS-2DPAGE; D5E926.
KW   Hydrolase {ECO:0000313|EMBL:ADE35677.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transferase {ECO:0000313|EMBL:ADE35677.1}.
FT   DOMAIN          14..129
FT                   /note="MGS"
FT                   /evidence="ECO:0000259|SMART:SM00851"
SQ   SEQUENCE   538 AA;  60087 MW;  FD02D7C9853EDD58 CRC64;
     MVKRALLSVS DKTGIVDFAR GLKQLDVEII STGGTARMLR DAGIETIDVS EITGFPEMMG
     GRVKTLHPKI HGGLLCLREN PEHVSDAEDL SIELIDMVVV NLYPFEITIS REGVNLEEAI
     ENIDIGGPSM LRSAAKNYKS VTVLSDPEDY GHILKELRSS GVVSRETREK MAVKAFRHTA
     NYDSTIDTYL SRTLLGEDIL RLNFTGGREL RYGENWHQEA LFFSQPEIEG PSLANCRQLH
     GKELSYNNYV DGDNALQTVK ELGQEKPAVC IVKHNNPCGL ATGNTLLQAL QSAWDGDPIS
     AFGSIICTNV PMDLESAKFL KGKFVEIIIA PEFEHDALDF LKNKSKNLRL LELPQLNESF
     DAEFTYKYIA GGMLKQSRNI GLYDKWECVT ETPYPEEKKG LSEFCIAACK CTKSNAVNLS
     WEYDEGCYMM LAMGAGQPNR VDSIRKLCAT KARENLKEIY EREQPDIAFE EYCNSIFEQC
     VLASDAFFPF DDSIIHAAEN NIKYVVSPGG SIRDNEVIDT ANRLGVSLVF TGMRHFLH
//

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