(data stored in SCRATCH3701 zone)

SWISSPROT: D5E971_METMS

ID   D5E971_METMS            Unreviewed;       638 AA.
AC   D5E971;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 49.
DE   SubName: Full=Na+/solute symporter {ECO:0000313|EMBL:ADE35722.1};
GN   OrderedLocusNames=Mmah_0187 {ECO:0000313|EMBL:ADE35722.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35722.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE35722.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC       family. {ECO:0000256|RuleBase:RU362091}.
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DR   EMBL; CP001994; ADE35722.1; -; Genomic_DNA.
DR   RefSeq; WP_013036665.1; NC_014002.1.
DR   EnsemblBacteria; ADE35722; ADE35722; Mmah_0187.
DR   GeneID; 8982318; -.
DR   KEGG; mmh:Mmah_0187; -.
DR   eggNOG; arCOG01316; Archaea.
DR   eggNOG; COG0591; LUCA.
DR   HOGENOM; HOG000226368; -.
DR   KO; K03307; -.
DR   OMA; LGANWLT; -.
DR   OrthoDB; 8968at2157; -.
DR   BioCyc; MMAH547558:G1GHT-187-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1730.10; -; 1.
DR   InterPro; IPR038377; Na/Glc_symporter_sf.
DR   InterPro; IPR001734; Na/solute_symporter.
DR   InterPro; IPR018212; Na/solute_symporter_CS.
DR   Pfam; PF00474; SSF; 1.
DR   PROSITE; PS00457; NA_SOLUT_SYMP_2; 1.
DR   PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5E971.
DR   SWISS-2DPAGE; D5E971.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        267..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        312..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        426..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        467..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   638 AA;  68477 MW;  1331D5565A7C42E0 CRC64;
     MESSQLFLIL LAVYLVGLIG IGWYFTKKQN TVTDFWLAGR RIGTVGVGFS SAASWLTAGG
     LLAVIAFFML QGMGSIWGFV APNILALLII AIFVKKIKNL PAITQAELLE QRYSSAIRAP
     IGIIITIVMI LFAVADIKGF ALVLETFYGF DPLYAALIVA LAVSVYVTLG GLSAVVWTDV
     VQFLFLSVFT IVIAIVSVGA ATGGAVDAPA NAGELFSNVS SGWWNPLSIG IPMVLIFLFA
     IVPGWITEQD PWQKVWAARD SKSARNGLLL GSLLITIVFA GCAVIAIALS SIYPEIPAAG
     FPMGMAQAEP ALLVFVLENF SPFIVALSAI GLAAAAMSCT DTFATSGASC VSRDIYQRFI
     KPDATMKQML AVNRLSVLFI VLAATVGSFF ITSILEAIHI ATYIASASYF FPLMGGLYWK
     RATKEGAMAG LIVGAVVQIS LIVYDIYMTA PMAPAYLQTV HPVLMNHGVI AGMGLSAVAF
     FGVSLLTKPS SAVNLAPFFK EEAKNLAAEA AVTVEEDDPK FQKFLKRIDE QLVGERAHLH
     VRLESSASVN WHRFVEALRS SYAAWVTPTG VDSVYRLVQA DMLSCVSITR GTTDKEIWFA
     SEPPASEMGD QKKELFVAYN EVAAALESMG VILTVVEE
//

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