(data stored in SCRATCH3701 zone)

SWISSPROT: D5E9S6_METMS

ID   D5E9S6_METMS            Unreviewed;       536 AA.
AC   D5E9S6;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 46.
DE   RecName: Full=60 kDa chaperonin {ECO:0000256|HAMAP-Rule:MF_00600};
DE   AltName: Full=GroEL protein {ECO:0000256|HAMAP-Rule:MF_00600};
DE   AltName: Full=Protein Cpn60 {ECO:0000256|HAMAP-Rule:MF_00600};
GN   Name=groL {ECO:0000256|HAMAP-Rule:MF_00600};
GN   Synonyms=groEL {ECO:0000256|HAMAP-Rule:MF_00600};
GN   OrderedLocusNames=Mmah_0395 {ECO:0000313|EMBL:ADE35927.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE35927.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE35927.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Prevents misfolding and promotes the refolding and proper
CC       assembly of unfolded polypeptides generated under stress conditions.
CC       {ECO:0000256|HAMAP-Rule:MF_00600}.
CC   -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7
CC       subunits. {ECO:0000256|HAMAP-Rule:MF_00600}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00600}.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC       {ECO:0000256|HAMAP-Rule:MF_00600, ECO:0000256|RuleBase:RU000418}.
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DR   EMBL; CP001994; ADE35927.1; -; Genomic_DNA.
DR   RefSeq; WP_013036870.1; NC_014002.1.
DR   EnsemblBacteria; ADE35927; ADE35927; Mmah_0395.
DR   GeneID; 8982530; -.
DR   KEGG; mmh:Mmah_0395; -.
DR   eggNOG; arCOG05154; Archaea.
DR   eggNOG; COG0459; LUCA.
DR   HOGENOM; HOG000076290; -.
DR   KO; K04077; -.
DR   OMA; TDTDKME; -.
DR   OrthoDB; 10544at2157; -.
DR   BioCyc; MMAH547558:G1GHT-392-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR   CDD; cd03344; GroEL; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   HAMAP; MF_00600; CH60; 1.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5E9S6.
DR   SWISS-2DPAGE; D5E9S6.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Chaperone {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00600};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
SQ   SEQUENCE   536 AA;  57669 MW;  BF6E033C85909EE4 CRC64;
     MTTKQITFDE NARQALLAGI DKVSNTVKVT LGPKGRNVVL DKSGNPTVTN DGVTIAKEIE
     LKDKFENMGA KLVKEVASRT QDNTGDGTTT ATLLAQAMIS EGIRNITAGA NPIEIKRGID
     KATAKVVEYL QTQSKEVKDR ERIIQVGTIS ANNDEEIGKL ISDAMDRVGY NGVITVDDSK
     TMETSLEVVE GMQFDRGYVS PYMATDQEKM VCELENPYIL LTDKKINNVN QIVPVLEKVA
     QEGKPLLIVA QDVEGDAQAA LILNIMRGSL KVSAVKAPGF GNDQKDMLED LAALTGGTVV
     SEDKGMKLED VTDDMLGSAH KVSVDKQKTT IIEGKGDKNA IESRMEMIES QINITDAEYK
     KKELQKRLAK LGGGVAVIKV GAATETELEE KKMRIDDALN ATKAAVEEGV VAGGGVTLFH
     AIPYLEKIEL EEDQMVGANI VKKALEAPLR QIAHNAGKEG AEVIALIKAE ADEEVGYNAK
     KGIVENLYNA GVIDPTKVVR SGLQNAASIA GMVLSTEALV AEYDEEKDEN APAIII
//

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