(data stored in SCRATCH3701 zone)

SWISSPROT: D5EA19_METMS

ID   D5EA19_METMS            Unreviewed;       196 AA.
AC   D5EA19;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 37.
DE   RecName: Full=GTP-dependent dephospho-CoA kinase {ECO:0000256|HAMAP-Rule:MF_00590};
DE            EC=2.7.1.- {ECO:0000256|HAMAP-Rule:MF_00590};
DE   AltName: Full=Dephospho-coenzyme A kinase {ECO:0000256|HAMAP-Rule:MF_00590};
DE            Short=DPCK {ECO:0000256|HAMAP-Rule:MF_00590};
GN   OrderedLocusNames=Mmah_0492 {ECO:0000313|EMBL:ADE36020.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36020.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36020.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of the 3'-
CC       hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
CC       {ECO:0000256|HAMAP-Rule:MF_00590, ECO:0000256|SAAS:SAAS01232535}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3'-dephospho-CoA + GTP = CoA + GDP + H(+);
CC         Xref=Rhea:RHEA:61156, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57328, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00590,
CC         ECO:0000256|SAAS:SAAS01232533};
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00590, ECO:0000256|SAAS:SAAS01232530}.
CC   -!- SIMILARITY: Belongs to the GTP-dependent DPCK family.
CC       {ECO:0000256|HAMAP-Rule:MF_00590, ECO:0000256|SAAS:SAAS01232529}.
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DR   EMBL; CP001994; ADE36020.1; -; Genomic_DNA.
DR   RefSeq; WP_013036963.1; NC_014002.1.
DR   EnsemblBacteria; ADE36020; ADE36020; Mmah_0492.
DR   GeneID; 8982633; -.
DR   KEGG; mmh:Mmah_0492; -.
DR   eggNOG; arCOG04076; Archaea.
DR   eggNOG; COG1909; LUCA.
DR   HOGENOM; HOG000229337; -.
DR   KO; K09735; -.
DR   OMA; AIYDHKT; -.
DR   OrthoDB; 116732at2157; -.
DR   BioCyc; MMAH547558:G1GHT-493-MONOMER; -.
DR   UniPathway; UPA00241; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00590; UPF0218; 1.
DR   InterPro; IPR007164; GTP-dep_dephospho-CoA_kin.
DR   PANTHER; PTHR40732; PTHR40732; 1.
DR   Pfam; PF04019; DUF359; 1.
DR   PIRSF; PIRSF006533; UCP006533; 1.
PE   3: Inferred from homology;
DR   PRODOM; D5EA19.
DR   SWISS-2DPAGE; D5EA19.
KW   Coenzyme A biosynthesis {ECO:0000256|HAMAP-Rule:MF_00590,
KW   ECO:0000256|SAAS:SAAS01232532};
KW   Kinase {ECO:0000256|HAMAP-Rule:MF_00590, ECO:0000256|SAAS:SAAS01232528};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00590,
KW   ECO:0000256|SAAS:SAAS01232531}.
SQ   SEQUENCE   196 AA;  21679 MW;  A618322A7C4D3C15 CRC64;
     MGGRISIPAS LRPLLRKKFG VLYKGSGEET VGKVSGDLGD PIKLISVGDV TTFHLLKSNI
     IPDILVIDDK THRQPACEQM ITGTKQSGFK ELVVNNPAGS ITEELVDAFA EALDSNRRVR
     IFVQGEEDLA SLPAIMMAPA GSVVLYGQPG EGMMFVRITA SKKEEMTELI DKIIDKQHCK
     EQLYTMWRKL YGYQHN
//

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