(data stored in SCRATCH3701 zone)

SWISSPROT: D5EA41_METMS

ID   D5EA41_METMS            Unreviewed;       402 AA.
AC   D5EA41;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   11-DEC-2019, entry version 47.
DE   SubName: Full=Phosphopantothenoylcysteine decarboxylase Phosphopantothenate-cysteine ligase {ECO:0000313|EMBL:ADE36042.1};
DE            EC=4.1.1.36 {ECO:0000313|EMBL:ADE36042.1};
DE            EC=6.3.2.5 {ECO:0000313|EMBL:ADE36042.1};
GN   OrderedLocusNames=Mmah_0515 {ECO:0000313|EMBL:ADE36042.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36042.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36042.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001994; ADE36042.1; -; Genomic_DNA.
DR   RefSeq; WP_013036985.1; NC_014002.1.
DR   EnsemblBacteria; ADE36042; ADE36042; Mmah_0515.
DR   GeneID; 8982656; -.
DR   KEGG; mmh:Mmah_0515; -.
DR   eggNOG; arCOG01704; Archaea.
DR   eggNOG; COG0452; LUCA.
DR   HOGENOM; HOG000037525; -.
DR   KO; K13038; -.
DR   OMA; VFAPAMH; -.
DR   OrthoDB; 56027at2157; -.
DR   BioCyc; MMAH547558:G1GHT-517-MONOMER; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
DR   GO; GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.10300; -; 1.
DR   Gene3D; 3.40.50.1950; -; 1.
DR   InterPro; IPR035929; CoaB-like_sf.
DR   InterPro; IPR005252; CoaBC.
DR   InterPro; IPR007085; DNA/pantothenate-metab_flavo_C.
DR   InterPro; IPR036551; Flavin_trans-like.
DR   InterPro; IPR003382; Flavoprotein.
DR   Pfam; PF04127; DFP; 1.
DR   Pfam; PF02441; Flavoprotein; 1.
DR   SUPFAM; SSF102645; SSF102645; 1.
DR   SUPFAM; SSF52507; SSF52507; 1.
DR   TIGRFAMs; TIGR00521; coaBC_dfp; 1.
PE   4: Predicted;
DR   PRODOM; D5EA41.
DR   SWISS-2DPAGE; D5EA41.
KW   Ligase {ECO:0000313|EMBL:ADE36042.1}; Lyase {ECO:0000313|EMBL:ADE36042.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT   DOMAIN          18..185
FT                   /note="Flavoprotein"
FT                   /evidence="ECO:0000259|Pfam:PF02441"
FT   DOMAIN          192..373
FT                   /note="DFP"
FT                   /evidence="ECO:0000259|Pfam:PF04127"
SQ   SEQUENCE   402 AA;  42659 MW;  D8766EB9BB45EF42 CRC64;
     MHSTLWIKGT KSKSLEGKTV VLAVTGSIAA VRVVELAREL IRNGANVYAV MSEAATRILH
     PDALHYATGH EVITDITGGV EHVGMCGLQG MADLLLIAPA TANTISKIAM GIDDTPVTTF
     ATTAIGSGVA TIVVPAMHQS MYDHPAVNSN LEKLGSYGIS LVGPRVEEGI AKIAPNDDIV
     LAVERELMGK KLAGKKIVLT SGATAEAIDP IRIITNRASG KTGQELAREA FRRGGDVTII
     HRNELDADGI NEVYAESAAS MLDSCMEEIG RGCDVFISSA AISDYTLDSL GSKIKSGQKL
     ILEMHPTEKI LPQVRSNYPA IVTVGFKAET GVGEKELVGS ATRMLEEYGL DMVVANDVMA
     GGMGTSENSI YILQDESSAS HYSGSKRYLA SIIMDRVEQI LL
//

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