(data stored in ACNUC1104 zone)

SWISSPROT: D5UQJ6_TSUPD

ID   D5UQJ6_TSUPD            Unreviewed;      1704 AA.
AC   D5UQJ6;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   08-MAY-2019, entry version 53.
DE   SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:ADG76829.1};
GN   OrderedLocusNames=Tpau_0175 {ECO:0000313|EMBL:ADG76829.1};
OS   Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 /
OS   NBRC 16120 / NCTC 13040) (Corynebacterium paurometabolum).
OC   Bacteria; Actinobacteria; Corynebacteriales; Tsukamurellaceae;
OC   Tsukamurella.
OX   NCBI_TaxID=521096 {ECO:0000313|EMBL:ADG76829.1, ECO:0000313|Proteomes:UP000001213};
RN   [1] {ECO:0000313|Proteomes:UP000001213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040
RC   {ECO:0000313|Proteomes:UP000001213};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Munk A.C., Brettin T., Detter J.C.,
RA   Tapia R., Han C., Larimer F., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Jando M., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete chromosome of Tsukamurella paurometabola DSM 20162.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADG76829.1, ECO:0000313|Proteomes:UP000001213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040
RC   {ECO:0000313|Proteomes:UP000001213};
RX   PubMed=21886861;
RA   Munk A.C., Lapidus A., Lucas S., Nolan M., Tice H., Cheng J.F.,
RA   Del Rio T.G., Goodwin L., Pitluck S., Liolios K., Huntemann M.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA   Palaniappan K., Tapia R., Han C., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Brettin T., Yasawong M., Brambilla E.M., Rohde M.,
RA   Sikorski J., Goker M., Detter J.C., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Tsukamurella paurometabola type strain
RT   (no. 33).";
RL   Stand. Genomic Sci. 4:342-351(2011).
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DR   EMBL; CP001966; ADG76829.1; -; Genomic_DNA.
DR   RefSeq; WP_013124884.1; NC_014158.1.
DR   STRING; 521096.Tpau_0175; -.
DR   EnsemblBacteria; ADG76829; ADG76829; Tpau_0175.
DR   KEGG; tpr:Tpau_0175; -.
DR   eggNOG; ENOG4108JVE; Bacteria.
DR   eggNOG; COG3319; LUCA.
DR   HOGENOM; HOG000046292; -.
DR   KO; K12437; -.
DR   OMA; QHRKMAK; -.
DR   OrthoDB; 1123553at2; -.
DR   BioCyc; TPAU521096:G1GKO-174-MONOMER; -.
DR   Proteomes; UP000001213; Chromosome.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 2.
DR   Gene3D; 3.40.47.10; -; 1.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR032821; KAsynt_C_assoc.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR001031; Thioesterase.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF16197; KAsynt_C_assoc; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF00550; PP-binding; 2.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SMART; SM00823; PKS_PP; 2.
DR   SUPFAM; SSF47336; SSF47336; 2.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   SUPFAM; SSF53901; SSF53901; 1.
DR   SUPFAM; SSF55048; SSF55048; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
DR   PROSITE; PS50075; CARRIER; 2.
PE   4: Predicted;
DR   PRODOM; D5UQJ6.
DR   SWISS-2DPAGE; D5UQJ6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001213};
KW   Phosphopantetheine {ECO:0000256|PROSITE-ProRule:PRU00258};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001213}.
FT   DOMAIN       20     97       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     1192   1266       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   MOD_RES      57     57       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
FT   MOD_RES    1226   1226       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
SQ   SEQUENCE   1704 AA;  183470 MW;  84A1631935C8DE0A CRC64;
     MAENEYTPHE GPTGKAREDL SLEELRAWMR QWIADATKQP VENITDDKSL DEFGLGSRDA
     VSMASDIEDF TGVQLTATVA FQHPTIALLS QRIIDGDPVV SDDDLAAEAA QYDRGEEFEA
     NRGTHDVAVV GLATRFPKAG ETPESTWEFL IGNGDATTDL PEDRWLEFKQ DPRLKAVLDE
     ANTFGGYLDD VASFDAEFFQ MTPREVEMVD PQQRLALELT WEALEQANIP PSSVKGTRTG
     VWMGSSANDY QMLAVADPTK ANPYALTGTS TSIVANRVSY FYDFHGPSVA VDTACSSSLV
     AIHQAIRSLR DGETDMAVAG GVNMLIVPAA TLGFDSLGAQ APDGKIKAFS SDANGMIRAE
     GGGVVLLKRL ADAERDGDDI LGVIAGSAVT SDGKSNGIFA PNPEAQVINL RDAYIDAGID
     PRTVDYLEAH GTGTILGDPL EADAIGRVLG RGRDAEKPLL LGSAKTNFGH LEAAAGIAGV
     AKVLLSIRNG QIPASLNFAG PNPYIQFEAN RLLMAARNTE WPRYSGHRIA GVTGNGFGGT
     NAHVVITEYI APEIVEGETE ADAADSADPN AVPEFYAATA DGVAVPLVLT AYVPSRRRAA
     AAELLEWLES DEATQYSLAE IGRTLASRNH GRVRSVVLAK DLDEAIKGFR AIAEGKNAPN
     VISANQPDAT GPAFIFSGFG SHHRKMAKQL YLENPVFKHY FDEVNELIID ESGDDYAEMI
     TDDAQTFHIE TGQVGIFAIQ VALVGLFRHH GIEPGVVLPH SMGEATAAWL TGGLSLEDAV
     RVICNRSRLM GEGEAMLPEE MERFMALVEY SADDIDTVLG EYEGLEICVY AAPTHTVIGG
     PGKVIDQIVA ETEAKGLMAR KLVTRGASHT SQMDPLLGEL QAELMGIEPH PLKYPMYSTV
     NKEEFYRAGH APVHDVDYWI KGLRHSVWFT QAVEKAVEAG YRTFIEFSPN PITLISVAAV
     TFGSGIQDAA LVQTLKRKED EPGTIMTALA TVFAHGHHVD VASLFGPGRY APVPRTKFQR
     KHIWIQTKLP DGGSGMVPGA HVALPDGRHV WQLDAGALTL GDQTRISLVD LAKNAAVQVL
     DGAAVTAAVE HGEAADGNTL TTTLTPHPGG ASIQVHENTG TGFRLLLDAV VVGGEASGSA
     AAPLITKAAP AAIADDADDA LDAEPAIAVS EETEAPAPEG SSTERWSPES GETVEHRLGV
     IIAETMGFEI EDLPKEIPLI DLGMDSLIAM RIKNRAEYEF DIPPIQIQAV RDASFNDVVQ
     FVEYAVEHRD QVDALAEHQS GTGEMADAGK LAEMMQAAKD EAAAKASAPE SAPESEPAAP
     SEPETGSDAP DLLDGAAVAE AIGDGVPPRD AAERLTFATY AIVVGRSPGG VFNELDVLSE
     DVAEKLTARL SERAGGEVDI EDVIDSKNIE EMATYVGAVM NEATPVDGFV RTLRKPENTN
     RKPLFLFHPA GGNTTAYEAL LRKLPQDLPV YGFERVEGEV EDRVREYLPK LKQIQPEGPY
     RLAGWSLGGA FAYGLGRALE DEGQQVEYIG LLDVVAPTVP LTDEPAEKKA RLQRWETFAR
     KNYDIGSEIE LPMDRLEAAD DEGQFKIIME LVQLSDKKVP TSMIEHQRTS FIDNRMLIKV
     NPADYGRFEG KVTLYRADRM HDGAVELEPN FADIAPDGGW APVVEDLEIV KIGGDHLQII
     DEPYIGKIAT HMSAELERAD AERS
//

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