(data stored in ACNUC7421 zone)

SWISSPROT: D6ZC24_SEGRD

ID   D6ZC24_SEGRD            Unreviewed;       424 AA.
AC   D6ZC24;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   RecName: Full=Deferrochelatase/peroxidase {ECO:0000256|RuleBase:RU365017};
DE            EC=1.11.1.- {ECO:0000256|RuleBase:RU365017};
GN   OrderedLocusNames=Srot_0517 {ECO:0000313|EMBL:ADG97001.1};
OS   Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 /
OS   DSM 44985 / JCM 13578).
OC   Bacteria; Actinobacteria; Corynebacteriales; Segniliparaceae;
OC   Segniliparus.
OX   NCBI_TaxID=640132 {ECO:0000313|EMBL:ADG97001.1, ECO:0000313|Proteomes:UP000002247};
RN   [1] {ECO:0000313|EMBL:ADG97001.1, ECO:0000313|Proteomes:UP000002247}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578
RC   {ECO:0000313|Proteomes:UP000002247};
RX   PubMed=21304703; DOI=10.4056/sigs.791633;
RA   Sikorski J., Lapidus A., Copeland A., Misra M., Glavina Del Rio T.,
RA   Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Jando M.,
RA   Schneider S., Bruce D., Goodwin L., Pitluck S., Liolios K.,
RA   Mikhailova N., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Chertkov O., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Brettin T., Detter J.C., Han C., Rohde M., Goker M.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Klenk H.P.;
RT   "Complete genome sequence of Segniliparus rotundus type strain (CDC
RT   1076).";
RL   Stand. Genomic Sci. 2:203-211(2010).
CC   -!- FUNCTION: Involved in the recovery of exogenous heme iron.
CC       Extracts iron from heme while preserving the tetrapyrrol ring
CC       intact. {ECO:0000256|RuleBase:RU365017}.
CC   -!- COFACTOR:
CC       Name=heme b; Xref=ChEBI:CHEBI:60344;
CC         Evidence={ECO:0000256|RuleBase:RU365017};
CC       Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group non-
CC       covalently per subunit. {ECO:0000256|RuleBase:RU365017};
CC   -!- SIMILARITY: Belongs to the DyP-type peroxidase family.
CC       {ECO:0000256|RuleBase:RU365017}.
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DR   EMBL; CP001958; ADG97001.1; -; Genomic_DNA.
DR   RefSeq; WP_013137457.1; NC_014168.1.
DR   STRING; 640132.Srot_0517; -.
DR   EnsemblBacteria; ADG97001; ADG97001; Srot_0517.
DR   KEGG; srt:Srot_0517; -.
DR   eggNOG; ENOG4105DBE; Bacteria.
DR   eggNOG; COG2837; LUCA.
DR   HOGENOM; HOG000236940; -.
DR   KO; K16301; -.
DR   OMA; QACANDP; -.
DR   OrthoDB; 837319at2; -.
DR   BioCyc; SROT640132:G1GLH-520-MONOMER; -.
DR   Proteomes; UP000002247; Chromosome.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0033212; P:iron import into cell; IEA:InterPro.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR006314; Dyp_peroxidase.
DR   InterPro; IPR006313; EfeB.
DR   InterPro; IPR006311; TAT_signal.
DR   Pfam; PF04261; Dyp_perox; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   TIGRFAMs; TIGR01413; Dyp_perox_fam; 1.
DR   TIGRFAMs; TIGR01412; tat_substr_1; 1.
DR   PROSITE; PS51404; DYP_PEROXIDASE; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
DR   PRODOM; D6ZC24.
DR   SWISS-2DPAGE; D6ZC24.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002247};
KW   Heme {ECO:0000256|RuleBase:RU365017};
KW   Iron {ECO:0000256|RuleBase:RU365017};
KW   Metal-binding {ECO:0000256|RuleBase:RU365017};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU365017};
KW   Peroxidase {ECO:0000256|RuleBase:RU365017,
KW   ECO:0000313|EMBL:ADG97001.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002247}.
SQ   SEQUENCE   424 AA;  45668 MW;  345706F31C4738D5 CRC64;
     MNNSLEPRYS RRQLLAVGGA SAVVAAGAGA AAGRAHIPER AAAGSDRDGV VPFRAAHQAG
     IVTAQQDQLH FAALDVMTES REELVALIKQ WTVMAERMTK GQEATPGGAM GGNPLAPPQD
     TGEAFDLAPA QLTITVGFGP GIFEKDGKDR FGLAKHRPEP LTPLPGFPGD ALEPARCGGD
     VVIQACANDP QVAVHAVRNL VRTGFGVVSV RWSQLGFGRT SSTSTRQVTP RNLFGFKDGT
     NNIKAEETNE LDKHIWVAKD DGPDWLVGGT YLVARRIRMN IERWDRDFLK DQEQTIGRTK
     ESGAPLSGGG EFEPLDLDAK LGVEPAIPWN AHVRLASHQN LGGIRILRRG YNFTDGSDGV
     GHLDAGLFFL AFCRDPQKQF VPMQQTLAKS DALNEYIKHT GSALFVCPPG LGDGEYWGQK
     LFEG
//

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