(data stored in ACNUC1104 zone)

SWISSPROT: D7A0U3_STAND

ID   D7A0U3_STAND            Unreviewed;       361 AA.
AC   D7A0U3;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 46.
DE   RecName: Full=Aldose 1-epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE            EC=5.1.3.3 {ECO:0000256|PIRNR:PIRNR005096};
DE   AltName: Full=Galactose mutarotase {ECO:0000256|PIRNR:PIRNR005096};
GN   OrderedLocusNames=Snov_0116 {ECO:0000313|EMBL:ADH87453.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87453.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87453.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
CC   -!- FUNCTION: Converts alpha-aldose to the beta-anomer.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose = beta-D-glucose; Xref=Rhea:RHEA:10264,
CC         ChEBI:CHEBI:15903, ChEBI:CHEBI:17925; EC=5.1.3.3;
CC         Evidence={ECO:0000256|PIRNR:PIRNR005096};
CC   -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
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DR   EMBL; CP002026; ADH87453.1; -; Genomic_DNA.
DR   RefSeq; WP_013164958.1; NC_014217.1.
DR   STRING; 639283.Snov_0116; -.
DR   EnsemblBacteria; ADH87453; ADH87453; Snov_0116.
DR   KEGG; sno:Snov_0116; -.
DR   eggNOG; ENOG4105ENN; Bacteria.
DR   eggNOG; COG2017; LUCA.
DR   HOGENOM; HOG000072798; -.
DR   KO; K01785; -.
DR   OMA; ATWLSCK; -.
DR   OrthoDB; 1512477at2; -.
DR   BioCyc; SNOV639283:G1GLM-116-MONOMER; -.
DR   UniPathway; UPA00242; -.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR015443; Aldose_1-epimerase.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   PIRSF; PIRSF005096; GALM; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
PE   3: Inferred from homology;
DR   PRODOM; D7A0U3.
DR   SWISS-2DPAGE; D7A0U3.
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR005096,
KW   ECO:0000313|EMBL:ADH87453.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633}.
FT   ACT_SITE    187    187       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   ACT_SITE    326    326       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   BINDING     260    260       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR005096-2}.
SQ   SEQUENCE   361 AA;  38808 MW;  FDA5731AA04EEBC2 CRC64;
     MHAAAHASPL LREPFGTLSD GRAVERIRLA GEGGFEVAII THGAAVQALH VPDRDGRLAD
     IVLGHDDLAP YEAHRRYFGA AVGRYANRIA GGRFPLDGTT CQVPANNGAN ALHGGPDGFD
     RRLWSVEALA DGSVPSVTLG LTSPDGDQGF PGELDVRVTY ALTGPRELSI AFEATTSRPT
     IVNLTHHGFF NLAGVEAGGD VLGHELTLHA DAYLPIDAAA IPVGGPTPVA GTPFDFRIPR
     LIGGRIREAH EQLRLGRGYD HNFCVAGGRT AEPRLAARVE HPASGRVLEL LTDQPGLQFY
     SGNFLDGTTE GKFRRLHRQS DAFCLEPQAW PDTPNRPNFP SARLDPGETY RHVSLYRFST
     V
//

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