SWISSPROT: D7A1W0_STAND

ID   D7A1W0_STAND            Unreviewed;       333 AA.
AC   D7A1W0;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 47.
DE   SubName: Full=Glyoxylate reductase {ECO:0000313|EMBL:ADH87576.1};
DE            EC=1.1.1.26 {ECO:0000313|EMBL:ADH87576.1};
GN   OrderedLocusNames=Snov_0241 {ECO:0000313|EMBL:ADH87576.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87576.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87576.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002026; ADH87576.1; -; Genomic_DNA.
DR   RefSeq; WP_013165081.1; NC_014217.1.
DR   STRING; 639283.Snov_0241; -.
DR   EnsemblBacteria; ADH87576; ADH87576; Snov_0241.
DR   KEGG; sno:Snov_0241; -.
DR   eggNOG; ENOG4105C5I; Bacteria.
DR   eggNOG; COG1052; LUCA.
DR   HOGENOM; HOG000136700; -.
DR   KO; K00015; -.
DR   OMA; YGAGVDH; -.
DR   OrthoDB; 1638924at2; -.
DR   BioCyc; SNOV639283:G1GLM-243-MONOMER; -.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0047964; F:glyoxylate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; D7A1W0.
DR   SWISS-2DPAGE; D7A1W0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW   ECO:0000313|EMBL:ADH87576.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633}.
FT   DOMAIN       17    328       2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.
FT   DOMAIN      113    297       2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
SQ   SEQUENCE   333 AA;  36600 MW;  F26F0B58D4635D66 CRC64;
     MARKKPLVVV TRRLPDKIET RMRELFDARL NVDDVPMSQE QLAEAMATAD VLVPAICDRI
     DAKVIEAAGP NLKLIANFGN GVDHIDVAAA NARGITVTNT PGVLTEDTAD MTMALILAVP
     RRLTEGAALI TSDDGTWPGW SPMWMLGHRI WGKRLGIIGM GRIGQAVARR AKAFGLQIHY
     HNRRPLPAHI EEDLEATYWD SLDQMLARMD ILSVNCPHTP ATFHLLSARR LKLIRPDAYI
     VNTARGEVID EHALIRMIEN GEIAGAGLDV FEREPAVSPK LLKLARAGKV VLLPHMGSAT
     VEARVDTGEK VIVNIKAFMD GHRPPDRVLP AML
//