(data stored in ACNUC1104 zone)

SWISSPROT: D7A262_STAND

ID   D7A262_STAND            Unreviewed;       260 AA.
AC   D7A262;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   08-MAY-2019, entry version 43.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase E {ECO:0000256|PIRNR:PIRNR015601};
DE            EC=2.1.1.193 {ECO:0000256|PIRNR:PIRNR015601};
GN   OrderedLocusNames=Snov_0345 {ECO:0000313|EMBL:ADH87678.1};
OS   Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 /
OS   NBRC 12443 / NCIB 9113).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Starkeya.
OX   NCBI_TaxID=639283 {ECO:0000313|EMBL:ADH87678.1, ECO:0000313|Proteomes:UP000006633};
RN   [1] {ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Beatson S., Kappler U.,
RA   Woyke T.;
RT   "Complete sequence of Starkeya novella DSM 506.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADH87678.1, ECO:0000313|Proteomes:UP000006633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB
RC   9113 {ECO:0000313|Proteomes:UP000006633};
RX   PubMed=23450099; DOI=10.4056/sigs.3006378;
RA   Kappler U., Davenport K., Beatson S., Lucas S., Lapidus A.,
RA   Copeland A., Berry K.W., Glavina Del Rio T., Hammon N., Dalin E.,
RA   Tice H., Pitluck S., Richardson P., Bruce D., Goodwin L.A., Han C.,
RA   Tapia R., Detter J.C., Chang Y.J., Jeffries C.D., Land M., Hauser L.,
RA   Kyrpides N.C., Goker M., Ivanova N., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of the facultatively chemolithoautotrophic
RT   and methylotrophic alpha Proteobacterium Starkeya novella type strain
RT   (ATCC 8093(T)).";
RL   Stand. Genomic Sci. 7:44-58(2012).
CC   -!- FUNCTION: Specifically methylates the N3 position of the uracil
CC       ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully
CC       assembled 30S ribosomal subunit. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-adenosyl-L-methionine + uridine(1498) in 16S rRNA =
CC         H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:42920, Rhea:RHEA-COMP:10283,
CC         Rhea:RHEA-COMP:10284, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:65315, ChEBI:CHEBI:74502;
CC         EC=2.1.1.193; Evidence={ECO:0000256|PIRNR:PIRNR015601};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase RsmE family.
CC       {ECO:0000256|PIRNR:PIRNR015601}.
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DR   EMBL; CP002026; ADH87678.1; -; Genomic_DNA.
DR   RefSeq; WP_013165183.1; NC_014217.1.
DR   STRING; 639283.Snov_0345; -.
DR   EnsemblBacteria; ADH87678; ADH87678; Snov_0345.
DR   KEGG; sno:Snov_0345; -.
DR   eggNOG; ENOG4105QF0; Bacteria.
DR   eggNOG; COG1385; LUCA.
DR   HOGENOM; HOG000015266; -.
DR   KO; K09761; -.
DR   OMA; ERMEFTI; -.
DR   OrthoDB; 1490892at2; -.
DR   BioCyc; SNOV639283:G1GLM-349-MONOMER; -.
DR   Proteomes; UP000006633; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR006700; rRNA_ssu_MeTrfase-E.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR30027; PTHR30027; 1.
DR   Pfam; PF04452; Methyltrans_RNA; 1.
DR   PIRSF; PIRSF015601; MTase_slr0722; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00046; TIGR00046; 1.
PE   3: Inferred from homology;
DR   PRODOM; D7A262.
DR   SWISS-2DPAGE; D7A262.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006633};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR015601};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR015601};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006633};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR015601};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR015601};
KW   Transferase {ECO:0000256|PIRNR:PIRNR015601}.
SQ   SEQUENCE   260 AA;  28754 MW;  72E70C533636CF79 CRC64;
     MARHQEDSSD QPYDFRAQRL YVDDDLGEGT LVRLDRDRAH YVADVIRLEV GGALHLFNGR
     DGEWRAVREP AGRREAVLRC EARLRRQAEP ADLDYVFAPL KHARLDYMVQ KAVEMGAGRL
     VPVMTRRTQA SRVNTERMRA NVIEAAEQCG ILSLPAVLEP SALARWLADL APERRLVFCD
     EAAPEADPLA ELREAVAGPL AVLIGPEGGF DEEERRLLKA RPGTIVLSLG PRILRADTAA
     VAALAMVEAA RQTAANFSAR
//

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