(data stored in ACNUC7421 zone)

SWISSPROT: D8FGB1_ASHGO

ID   D8FGB1_ASHGO            Unreviewed;        75 AA.
AC   D8FGB1;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   11-DEC-2019, entry version 41.
DE   RecName: Full=Dolichol phosphate-mannose biosynthesis regulatory protein {ECO:0000256|RuleBase:RU365084};
GN   ORFNames=AGOS_ACR063WA {ECO:0000313|EMBL:ADJ41754.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:ADJ41754.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:ADJ41754.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 10895;
RA   Dietrich F.S., Voegeli S., Philippsen P.;
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Regulatory subunit of the dolichol-phosphate mannose (DPM)
CC       synthase complex; essential for the ER localization.
CC       {ECO:0000256|RuleBase:RU365084}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|RuleBase:RU365084}.
CC   -!- SUBUNIT: Component of the dolichol-phosphate mannose (DPM) synthase
CC       complex. {ECO:0000256|RuleBase:RU365084}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU365084}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU365084}.
CC   -!- SIMILARITY: Belongs to the DPM2 family.
CC       {ECO:0000256|RuleBase:RU365084}.
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DR   EMBL; AE016816; ADJ41754.1; -; Genomic_DNA.
DR   RefSeq; XP_002999461.1; XM_002999415.1.
DR   STRING; 33169.ADJ41754; -.
DR   EnsemblFungi; ADJ41754; ADJ41754; AGOS_ACR063WA.
DR   KEGG; ago:AGOS_ACR063WA; -.
DR   HOGENOM; HOG000000962; -.
DR   InParanoid; D8FGB1; -.
DR   OMA; NRLTIWI; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019348; P:dolichol metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR009914; DPM2.
DR   Pfam; PF07297; DPM2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D8FGB1.
DR   SWISS-2DPAGE; D8FGB1.
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU365084};
KW   Membrane {ECO:0000256|RuleBase:RU365084};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Transmembrane {ECO:0000256|RuleBase:RU365084};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU365084}.
FT   TRANSMEM        5..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365084"
FT   TRANSMEM        35..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365084"
SQ   SEQUENCE   75 AA;  8433 MW;  3065B07A59F2E105 CRC64;
     MLKFALLLGI FSYYTAWLLL PIFDLDGKLW LFPLPSLYAV LLPIVLLLCG AFIVGSSLGA
     LLLTSKRNVD YVHYK
//

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