(data stored in SCRATCH zone)

SWISSPROT: A0A0F6BID3_GEOS0

ID   A0A0F6BID3_GEOS0        Unreviewed;        75 AA.
AC   A0A0F6BID3;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   11-DEC-2019, entry version 26.
DE   RecName: Full=Translational regulator CsrA {ECO:0000256|HAMAP-Rule:MF_00167, ECO:0000256|SAAS:SAAS00970184};
GN   Name=csrA {ECO:0000256|HAMAP-Rule:MF_00167};
GN   OrderedLocusNames=GY4MC1_0339 {ECO:0000313|EMBL:ADP73184.1};
OS   Geobacillus sp. (strain Y4.1MC1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   unclassified Geobacillus.
OX   NCBI_TaxID=581103 {ECO:0000313|EMBL:ADP73184.1};
RN   [1] {ECO:0000313|EMBL:ADP73184.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y4.1MC1 {ECO:0000313|EMBL:ADP73184.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Zhang X., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G., Brumm P.,
RA   Mead D., Woyke T.;
RT   "Complete sequence of chromosome of Geobacillus sp. Y4.1MC1.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: A translational regulator that binds mRNA to regulate
CC       translation initiation and/or mRNA stability. Usually binds in the 5'-
CC       UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding,
CC       thus repressing translation. Its main target seems to be the major
CC       flagellin gene, while its function is anatagonized by FliW.
CC       {ECO:0000256|HAMAP-Rule:MF_00167}.
CC   -!- SUBUNIT: Homodimer; the beta-strands of each monomer intercalate to
CC       form a hydrophobic core, while the alpha-helices form wings that extend
CC       away from the core. {ECO:0000256|HAMAP-Rule:MF_00167,
CC       ECO:0000256|SAAS:SAAS00970188}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00167,
CC       ECO:0000256|SAAS:SAAS00970186}.
CC   -!- SIMILARITY: Belongs to the CsrA/RsmA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00167, ECO:0000256|SAAS:SAAS00970183}.
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DR   EMBL; CP002293; ADP73184.1; -; Genomic_DNA.
DR   RefSeq; WP_013399964.1; NC_014650.1.
DR   EnsemblBacteria; ADP73184; ADP73184; GY4MC1_0339.
DR   KEGG; gmc:GY4MC1_0339; -.
DR   KO; K03563; -.
DR   OMA; IHRKEVY; -.
DR   OrthoDB; 2032250at2; -.
DR   BioCyc; GSP581103:G1GOQ-385-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:1902208; P:regulation of bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006109; P:regulation of carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.70.1680; -; 1.
DR   HAMAP; MF_00167; CsrA; 1.
DR   InterPro; IPR003751; CsrA.
DR   InterPro; IPR036107; CsrA_sf.
DR   PANTHER; PTHR34984; PTHR34984; 1.
DR   Pfam; PF02599; CsrA; 1.
DR   SUPFAM; SSF117130; SSF117130; 1.
DR   TIGRFAMs; TIGR00202; csrA; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0F6BID3.
DR   SWISS-2DPAGE; A0A0F6BID3.
KW   Bacterial flagellum biogenesis {ECO:0000256|HAMAP-Rule:MF_00167};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00167, ECO:0000256|SAAS:SAAS00970182};
KW   Repressor {ECO:0000256|HAMAP-Rule:MF_00167, ECO:0000256|SAAS:SAAS00970189};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00167,
KW   ECO:0000256|SAAS:SAAS00702517};
KW   Translation regulation {ECO:0000256|HAMAP-Rule:MF_00167,
KW   ECO:0000256|SAAS:SAAS00970191}.
SQ   SEQUENCE   75 AA;  8562 MW;  E05701FED8D2EA9E CRC64;
     MLVLTRKKNE SIMIGDSIEI KVLAIEGEQI KLGIIAPKHI DVYRKEIYTA IQEENKQAAD
     VSTNLLRQLK NNKKN
//

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