(data stored in ACNUC7421 zone)

SWISSPROT: E3J4R4_FRAIE

ID   E3J4R4_FRAIE            Unreviewed;       417 AA.
AC   E3J4R4;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   08-MAY-2019, entry version 47.
DE   RecName: Full=Glutamate dehydrogenase {ECO:0000256|PIRNR:PIRNR000185};
GN   OrderedLocusNames=FraEuI1c_0145 {ECO:0000313|EMBL:ADP78233.1};
OS   Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298654 {ECO:0000313|EMBL:ADP78233.1, ECO:0000313|Proteomes:UP000002484};
RN   [1] {ECO:0000313|EMBL:ADP78233.1, ECO:0000313|Proteomes:UP000002484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45817 / CECT 9037 / EuI1c
RC   {ECO:0000313|Proteomes:UP000002484};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Beauchemin N., Sen A., Sur S.A., Gtari M., Wall L., Tisa L., Woyke T.;
RT   "Complete sequence of Frankia sp. EuI1c.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
CC       {ECO:0000256|PIRNR:PIRNR000185, ECO:0000256|RuleBase:RU004417}.
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DR   EMBL; CP002299; ADP78233.1; -; Genomic_DNA.
DR   RefSeq; WP_013421356.1; NC_014666.1.
DR   STRING; 298654.FraEuI1c_0145; -.
DR   EnsemblBacteria; ADP78233; ADP78233; FraEuI1c_0145.
DR   KEGG; fri:FraEuI1c_0145; -.
DR   eggNOG; ENOG4107R37; Bacteria.
DR   eggNOG; COG0334; LUCA.
DR   HOGENOM; HOG000243801; -.
DR   KO; K00261; -.
DR   OMA; GSHGRES; -.
DR   OrthoDB; 1184827at2; -.
DR   BioCyc; FSP298654:G1GOT-148-MONOMER; -.
DR   Proteomes; UP000002484; Chromosome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   CDD; cd01076; NAD_bind_1_Glu_DH; 1.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DH.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DH_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DH_dimer_dom.
DR   InterPro; IPR014362; Glu_DH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR033922; NAD_bind_Glu_DH.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   SMART; SM00839; ELFV_dehydrog; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
DR   PRODOM; E3J4R4.
DR   SWISS-2DPAGE; E3J4R4.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002484};
KW   NAD {ECO:0000256|PIRSR:PIRSR000185-2};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000185-2};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000185,
KW   ECO:0000256|RuleBase:RU004417};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002484}.
FT   DOMAIN      183    414       ELFV_dehydrog. {ECO:0000259|SMART:
FT                                SM00839}.
FT   COILED      369    389       {ECO:0000256|SAM:Coils}.
FT   ACT_SITE    106    106       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR000185-1}.
FT   BINDING      70     70       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000185-2}.
FT   BINDING      94     94       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000185-2}.
FT   BINDING     190    190       NAD. {ECO:0000256|PIRSR:PIRSR000185-2}.
FT   BINDING     350    350       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000185-2}.
FT   SITE        146    146       Important for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR000185-3}.
SQ   SEQUENCE   417 AA;  44388 MW;  69324C4E1493FFC4 CRC64;
     MSLGSSPWDT ACVQLADAAR HLGLDEGMHD LLRMPRRSVT VSVPLRRDDG QLLVLTGYRV
     QHNLARGPAK GGIRFHPSTD LDEVKALAMW MTWKCALMGI PYGGAKGGIA VEPKMLSDQE
     RERMTRRYAA ELVPLIGPEK DIPAPDVGTD EQTMAWIMDT YSAHTGHTSH GVVTGKPLSV
     GGSAGRAGAT SRGVQLAMFA ALRERGLDPA DVSVAIQGFG KVGALAAQYL HDAGCRVVAV
     SDVKGGVYNP RGLNPTALIR HLARGADTVV GFPGTDTLSN SELLELDVDV LVPAALEGVI
     TAENAGRVRA RMIVEGANGP VAAEADPILA EKGVVVVPDI LANGGGVAVS YFEWVQDLQA
     YFWTEDQVNE RLAELMERAY AQVSRLAAER GLTLRAAAHV IGVGRVAEAH RTRGLYP
//

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