(data stored in ACNUC7421 zone)

SWISSPROT: E6SFG4_INTC7

ID   E6SFG4_INTC7            Unreviewed;       460 AA.
AC   E6SFG4;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   08-MAY-2019, entry version 45.
DE   SubName: Full=Tryptophanase {ECO:0000313|EMBL:ADU46702.1};
DE            EC=4.1.99.1 {ECO:0000313|EMBL:ADU46702.1};
GN   OrderedLocusNames=Intca_0141 {ECO:0000313|EMBL:ADU46702.1};
OS   Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 /
OS   NBRC 12989 / 7 KIP).
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Intrasporangium.
OX   NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU46702.1, ECO:0000313|Proteomes:UP000008914};
RN   [1] {ECO:0000313|EMBL:ADU46702.1, ECO:0000313|Proteomes:UP000008914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC   {ECO:0000313|Proteomes:UP000008914};
RX   PubMed=21304734; DOI=10.4056/sigs.1263355;
RA   Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S.,
RA   Cheng J.F., Detter C., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Rohde M., Pukall R., Sikorski J., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Intrasporangium calvum type strain (7
RT   KIP).";
RL   Stand. Genomic Sci. 3:294-303(2010).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR611166-50,
CC         ECO:0000256|SAAS:SAAS00170168};
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC       {ECO:0000256|SAAS:SAAS00559258}.
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DR   EMBL; CP002343; ADU46702.1; -; Genomic_DNA.
DR   RefSeq; WP_013491024.1; NC_014830.1.
DR   STRING; 710696.Intca_0141; -.
DR   EnsemblBacteria; ADU46702; ADU46702; Intca_0141.
DR   KEGG; ica:Intca_0141; -.
DR   eggNOG; ENOG4105C0F; Bacteria.
DR   eggNOG; COG3033; LUCA.
DR   HOGENOM; HOG000057883; -.
DR   KO; K01667; -.
DR   OrthoDB; 91973at2; -.
DR   BioCyc; ICAL710696:GH9U-145-MONOMER; -.
DR   Proteomes; UP000008914; Chromosome.
DR   GO; GO:0009034; F:tryptophanase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR011166; Beta-eliminating_lyase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF001386; Trpase; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
PE   3: Inferred from homology;
DR   PRODOM; E6SFG4.
DR   SWISS-2DPAGE; E6SFG4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008914};
KW   Lyase {ECO:0000256|SAAS:SAAS00257121, ECO:0000313|EMBL:ADU46702.1};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR611166-50,
KW   ECO:0000256|SAAS:SAAS00445674};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008914}.
FT   DOMAIN       51    425       Beta_elim_lyase. {ECO:0000259|Pfam:
FT                                PF01212}.
FT   MOD_RES     261    261       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR611166-50}.
SQ   SEQUENCE   460 AA;  50334 MW;  6AB12273C60937BD CRC64;
     MDDAPFTTII EPFRIHSVEP LTMTTRAERQ DHLRTAGYNL FQLRAQHVLI DLLTDSGTGA
     MSRDQWAAIQ HGDESYAGSP SYYVFVDAVR ELFPFEHVIP VHQGRAAEKI LFSALGGAGK
     VVPNNTHFDT TRANVEASGA SAVDLVIAEG RDPVSDHPFK GNMDLAALEA LLAARADDVP
     CVMVTITNNS GGGQPVSLEN LRGVREICDR YGKPLYLDAC RFAENAWFIR EREEGQGDRD
     VSDIVREISG LADGMTMSAK KDPMGNIGGW LAMNDDDLAQ RCRNTLILTE GFPTYGGLAG
     RDLEALAQGL REVVQHDYLR YRIRSTAYLG EALVKLGVPV LTPIGGHAVY IDARALAPHL
     SPLEYPGQAV AVALYELGGI RSCEIGTVMF GRQADGTEQP ASMELVRLAI PRRTYTQSHI
     DYVIEVCERL AAVAPSLPGY RITSEPPVLR HFTASFEPLR
//

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