SWISSPROT: E6S866_INTC7

ID   E6S866_INTC7            Unreviewed;       436 AA.
AC   E6S866;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   SubName: Full=Major facilitator superfamily MFS_1 {ECO:0000313|EMBL:ADU46970.1};
GN   OrderedLocusNames=Intca_0422 {ECO:0000313|EMBL:ADU46970.1};
OS   Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 /
OS   NBRC 12989 / 7 KIP).
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Intrasporangium.
OX   NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU46970.1, ECO:0000313|Proteomes:UP000008914};
RN   [1] {ECO:0000313|EMBL:ADU46970.1, ECO:0000313|Proteomes:UP000008914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC   {ECO:0000313|Proteomes:UP000008914};
RX   PubMed=21304734; DOI=10.4056/sigs.1263355;
RA   Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S.,
RA   Cheng J.F., Detter C., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Rohde M., Pukall R., Sikorski J., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Intrasporangium calvum type strain (7
RT   KIP).";
RL   Stand. Genomic Sci. 3:294-303(2010).
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DR   EMBL; CP002343; ADU46970.1; -; Genomic_DNA.
DR   RefSeq; WP_013491291.1; NC_014830.1.
DR   STRING; 710696.Intca_0422; -.
DR   EnsemblBacteria; ADU46970; ADU46970; Intca_0422.
DR   KEGG; ica:Intca_0422; -.
DR   eggNOG; ENOG4108PXX; Bacteria.
DR   eggNOG; ENOG410YH1B; LUCA.
DR   HOGENOM; HOG000053496; -.
DR   OrthoDB; 1452500at2; -.
DR   BioCyc; ICAL710696:GH9U-433-MONOMER; -.
DR   Proteomes; UP000008914; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG.
DR   Pfam; PF07690; MFS_1; 1.
DR   PRINTS; PR01035; TCRTETA.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; E6S866.
DR   SWISS-2DPAGE; E6S866.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008914};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008914};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     24     47       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     53     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    106       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    112    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    146    166       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    178    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    228    246       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    266    284       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    296    314       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    320    340       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    360    383       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    389    409       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    412       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   436 AA;  45702 MW;  948BC9FB14846239 CRC64;
     MSTHSTARPT LSSFWQDLPR DGKLLISTVV FQSIGTGLVL PFMVVYLNEV RGIALETVGL
     LLALQAGVGI AVVTPVGALI DRVGPRRVYA SSLVALILAD ILLARATTVN QASVALLLLG
     YGFGVVWPAS SALIGNLIPS ELRQRYFGVN FTLLNLGIGI GGIIGGRFVD VTRPDTFVAV
     YLLDALSYIP GLVILLGPLR HARDRVERAA DAASVRVSYR ALLRDPDLRA LLSLVAVAAL
     VSYPQLNAGL PAYARAEGQI STQGLGYAFA VNTLVIVLLQ LFVLQRIEGK RRTRVAVVMA
     GTWAVAWSLL GATSIVPGTI VATVLLAACT GIFGLGETML QPTTAAMVND LAPDHLRGRY
     NALSSLMFSI AFVVGPVIAS FLIGHDLGGG YIAFLVGGCA LLVIMALAAE RRLPAHVNGL
     RPAPGGSVTA PAPISG
//