(data stored in ACNUC13479 zone)

SWISSPROT: BH140_ARATH

ID   BH140_ARATH             Reviewed;         912 AA.
AC   Q9M041;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   07-JUN-2017, entry version 126.
DE   RecName: Full=Transcription factor bHLH140;
DE   AltName: Full=Basic helix-loop-helix protein 140;
DE            Short=AtbHLH140;
DE            Short=bHLH 140;
DE   AltName: Full=Transcription factor EN 122;
DE   AltName: Full=bHLH transcription factor bHLH140;
GN   Name=BHLH140; Synonyms=EN122; OrderedLocusNames=At5g01310;
GN   ORFNames=T10O8.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K.,
RA   Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S.,
RA   Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M.,
RA   Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R.,
RA   Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J.,
RA   Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M.,
RA   Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M.,
RA   Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P.,
RA   Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C.,
RA   Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N.,
RA   Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J.,
RA   Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S.,
RA   Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W.,
RA   Ramsperger U., Wedler H., Balke K., Wedler E., Peters S.,
RA   van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R.,
RA   Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W.,
RA   Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H.,
RA   Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12897250; DOI=10.1105/tpc.013839;
RA   Toledo-Ortiz G., Huq E., Quail P.H.;
RT   "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL   Plant Cell 15:1749-1770(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=14600211; DOI=10.1105/tpc.151140;
RA   Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E.,
RA   Heim M.A., Jakoby M., Werber M., Weisshaar B.;
RT   "Update on the basic helix-loop-helix transcription factor gene family
RT   in Arabidopsis thaliana.";
RL   Plant Cell 15:2497-2502(2003).
CC   -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
CC       ProRule:PRU00981}.
DR   EMBL; AL161746; CAB81914.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90326.1; -; Genomic_DNA.
DR   PIR; T48153; T48153.
DR   RefSeq; NP_195751.2; NM_120209.2.
DR   UniGene; At.54671; -.
DR   ProteinModelPortal; Q9M041; -.
DR   SMR; Q9M041; -.
DR   STRING; 3702.AT5G01310.1; -.
DR   iPTMnet; Q9M041; -.
DR   PaxDb; Q9M041; -.
DR   PRIDE; Q9M041; -.
DR   GeneID; 830940; -.
DR   KEGG; ath:AT5G01310; -.
DR   Araport; AT5G01310; -.
DR   TAIR; locus:2179122; AT5G01310.
DR   eggNOG; KOG0562; Eukaryota.
DR   eggNOG; KOG2134; Eukaryota.
DR   eggNOG; ENOG41102F4; LUCA.
DR   HOGENOM; HOG000083464; -.
DR   InParanoid; Q9M041; -.
DR   KO; K10863; -.
DR   OMA; ATNWRLK; -.
DR   OrthoDB; EOG093603GY; -.
DR   PhylomeDB; Q9M041; -.
DR   BioCyc; ARA:AT5G01310-MONOMER; -.
DR   PRO; PR:Q9M041; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   Genevisible; Q9M041; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0047627; F:adenylylsulfatase activity; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; ISS:TAIR.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0009150; P:purine ribonucleotide metabolic process; IDA:TAIR.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:TAIR.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   CDD; cd00083; HLH; 1.
DR   Gene3D; 3.30.428.10; -; 1.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR019808; Histidine_triad_CS.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032566; Znf-C2HE.
DR   Pfam; PF00010; HLH; 1.
DR   Pfam; PF01661; Macro; 1.
DR   Pfam; PF16278; zf-C2HE; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54197; SSF54197; 1.
DR   PROSITE; PS50888; BHLH; 1.
DR   PROSITE; PS00892; HIT_1; 1.
DR   PROSITE; PS51084; HIT_2; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9M041.
DR   SWISS-2DPAGE; Q9M041.
KW   ATP-binding; Complete proteome; DNA replication; DNA-binding;
KW   Metal-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN         1    912       Transcription factor bHLH140.
FT                                /FTId=PRO_0000358820.
FT   DOMAIN       43     92       bHLH. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00981}.
FT   DOMAIN      511    690       Macro. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00490}.
FT   DOMAIN      720    829       HIT. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00464}.
FT   NP_BIND     234    241       ATP. {ECO:0000255}.
FT   ZN_FING     870    893       C2H2-type.
SQ   SEQUENCE   912 AA;  101388 MW;  A2F400ED42A09457 CRC64;
     MDDFNLRSEN PNSSSTTSSS SSSFHRHKSE TGNTKRSRST STLSTDPQSV AARDRRHRIS
     DRFKILQSMV PGGAKMDTVS MLDEAISYVK FLKAQIWYHQ NMLLFINDHE TTSSCTYSPG
     AGEFGPKLFG YDDDYAPIMD TYSQGVPLTV ADSKYTPWFG SVDDEQEHVT YFKYRRATRH
     ALRGHCNCII GETEEFADQR EKMEVQIEES GKNQTSPESI EADKAKQIVV LLIGPPGSGK
     STFCDTAMRS SHRPWSRICQ DIVNNGKAGT KAQCLKMATD SLREGKSVFI DRCNLDREQR
     SEFIKLGGPE FEVHAVVLEL PAQVCISRSV KRTGHEGNLQ GGRAAAVVNK MLQSKELPKV
     NEGFSRIMFC YSDADVDNAV NMYNKLGPMD TLPSGCFGEK KLDTKSQPGI MKFFKKVSAL
     PASSSNEATN TTRKADEMTA NVRVSPVKLG SADIVPTLAF PSISTADFQF DLEKASDIIV
     EKAEEFLSKL GTARLVLVDL SRGSKILSLV KAKASQKNID SAKFFTFVGD ITKLRSEGGL
     HCNVIANATN WRLKPGGGGV NAAIFKAAGP DLETATRVRA NTLLPGKAVV VPLPSTCPLH
     NAEGITHVIH VLGPNMNPNR PDNLNNDYTK GCKTLREAYT SLFEGFLSVV QDQSKLPKRS
     SQTAVSDSGE DIKEDSERNK KYKGSQDKAV TNNLESESLE DTRGSGKKMS KGWNTWALAL
     HSIAMHPERH ENVVLEYLDN IVVINDQYPK ARKHVLVLAR QESLDGLEDV RKENLQLLQE
     MHNVGLKWVD RFQNEDASLI FRLGYHSVPS MRQLHLHVIS QDFNSDSLKN KKHWNSFTTS
     FFRDSVDVLE EVNSQGKANV ASEDLLKGEL RCNRCRSAHP NIPKLKSHVR SCHSQFPDHL
     LQNNRLVARA ET
//

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