(data stored in ACNUC13479 zone)

SWISSPROT: LOR15_ARATH

ID   LOR15_ARATH             Reviewed;         217 AA.
AC   Q9LZX1; Q8LEK9;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   30-AUG-2017, entry version 92.
DE   RecName: Full=Protein LURP-one-related 15;
GN   OrderedLocusNames=At5g01750; ORFNames=T20L15.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K.,
RA   Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S.,
RA   Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M.,
RA   Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R.,
RA   Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J.,
RA   Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M.,
RA   Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M.,
RA   Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P.,
RA   Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C.,
RA   Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N.,
RA   Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J.,
RA   Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S.,
RA   Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W.,
RA   Ramsperger U., Wedler H., Balke K., Wedler E., Peters S.,
RA   van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R.,
RA   Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W.,
RA   Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H.,
RA   Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RA   Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   FUNCTION.
RX   PubMed=19010806; DOI=10.1093/bioinformatics/btn595;
RA   Bateman A., Finn R.D., Sims P.J., Wiedmer T., Biegert A., Soding J.;
RT   "Phospholipid scramblases and Tubby-like proteins belong to a new
RT   superfamily of membrane tethered transcription factors.";
RL   Bioinformatics 25:159-162(2009).
RN   [6]
RP   ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22223895; DOI=10.1074/mcp.M111.015131;
RA   Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C.,
RA   Meinnel T., Giglione C.;
RT   "Comparative large-scale characterisation of plant vs. mammal proteins
RT   reveals similar and idiosyncratic N-alpha acetylation features.";
RL   Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
RN   [7]
RP   X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 1-217 (ISOFORM 1).
RG   Center for eukaryotic structural genomics (CESG);
RT   "X-ray structure of protein At5g01750 from Arabidopsis thaliana.";
RL   Submitted (JUN-2005) to the PDB data bank.
CC   -!- FUNCTION: Might be related to the phospholipid scramblase and
CC       tubby-like superfamily of membrane tethered transcription factors.
CC       {ECO:0000269|PubMed:19010806}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q9LZX1-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9LZX1-2; Sequence=VSP_018603, VSP_018604;
CC         Note=No experimental confirmation available.;
CC   -!- SIMILARITY: Belongs to the LOR family. {ECO:0000305}.
DR   EMBL; AL162351; CAB82745.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90386.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90387.1; -; Genomic_DNA.
DR   EMBL; AF372877; AAK49593.1; -; mRNA.
DR   EMBL; AY142034; AAM98298.1; -; mRNA.
DR   EMBL; AY085369; AAM62599.1; -; mRNA.
DR   PIR; T48196; T48196.
DR   RefSeq; NP_568095.1; NM_120253.4. [Q9LZX1-2]
DR   RefSeq; NP_850751.1; NM_180420.2. [Q9LZX1-1]
DR   UniGene; At.21392; -.
DR   PDB; 1ZXU; X-ray; 1.70 A; A=1-217.
DR   PDB; 2Q4M; X-ray; 1.70 A; A=1-217.
DR   PDBsum; 1ZXU; -.
DR   PDBsum; 2Q4M; -.
DR   ProteinModelPortal; Q9LZX1; -.
DR   SMR; Q9LZX1; -.
DR   BioGrid; 16960; 4.
DR   IntAct; Q9LZX1; 4.
DR   STRING; 3702.AT5G01750.2; -.
DR   iPTMnet; Q9LZX1; -.
DR   PaxDb; Q9LZX1; -.
DR   PRIDE; Q9LZX1; -.
DR   DNASU; 831684; -.
DR   EnsemblPlants; AT5G01750.1; AT5G01750.1; AT5G01750. [Q9LZX1-2]
DR   EnsemblPlants; AT5G01750.2; AT5G01750.2; AT5G01750. [Q9LZX1-1]
DR   GeneID; 831684; -.
DR   Gramene; AT5G01750.1; AT5G01750.1; AT5G01750.
DR   Gramene; AT5G01750.2; AT5G01750.2; AT5G01750.
DR   KEGG; ath:AT5G01750; -.
DR   Araport; AT5G01750; -.
DR   TAIR; locus:2181082; AT5G01750.
DR   eggNOG; ENOG410IKCI; Eukaryota.
DR   eggNOG; ENOG4111GT4; LUCA.
DR   HOGENOM; HOG000242212; -.
DR   InParanoid; Q9LZX1; -.
DR   OMA; CVCFDEK; -.
DR   OrthoDB; EOG09360OHK; -.
DR   PhylomeDB; Q9LZX1; -.
DR   EvolutionaryTrace; Q9LZX1; -.
DR   PRO; PR:Q9LZX1; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   Genevisible; Q9LZX1; AT.
DR   GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:CAFA.
DR   InterPro; IPR007612; LURP1-related.
DR   InterPro; IPR025659; Tubby_C-like.
DR   Pfam; PF04525; LOR; 1.
DR   SUPFAM; SSF54518; SSF54518; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q9LZX1.
DR   SWISS-2DPAGE; Q9LZX1.
KW   3D-structure; Acetylation; Alternative splicing; Complete proteome;
KW   Reference proteome.
FT   CHAIN         1    217       Protein LURP-one-related 15.
FT                                /FTId=PRO_0000238457.
FT   MOD_RES       1      1       N-acetylmethionine.
FT                                {ECO:0000244|PubMed:22223895}.
FT   VAR_SEQ     171    174       MHRK -> VYYL (in isoform 2).
FT                                {ECO:0000303|Ref.4}.
FT                                /FTId=VSP_018603.
FT   VAR_SEQ     175    217       Missing (in isoform 2).
FT                                {ECO:0000303|Ref.4}.
FT                                /FTId=VSP_018604.
FT   CONFLICT     31     31       K -> R (in Ref. 4; AAM62599).
FT                                {ECO:0000305}.
FT   CONFLICT    111    111       D -> E (in Ref. 4; AAM62599).
FT                                {ECO:0000305}.
FT   HELIX        30     32       {ECO:0000244|PDB:1ZXU}.
FT   STRAND       38     43       {ECO:0000244|PDB:1ZXU}.
FT   STRAND       54     58       {ECO:0000244|PDB:1ZXU}.
FT   STRAND       63     68       {ECO:0000244|PDB:1ZXU}.
FT   STRAND       76     81       {ECO:0000244|PDB:1ZXU}.
FT   STRAND       87     92       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      101    106       {ECO:0000244|PDB:1ZXU}.
FT   HELIX       112    114       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      115    120       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      131    135       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      145    150       {ECO:0000244|PDB:1ZXU}.
FT   TURN        152    155       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      158    161       {ECO:0000244|PDB:1ZXU}.
FT   TURN        162    164       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      167    173       {ECO:0000244|PDB:1ZXU}.
FT   STRAND      186    191       {ECO:0000244|PDB:1ZXU}.
FT   HELIX       197    211       {ECO:0000244|PDB:1ZXU}.
SQ   SEQUENCE   217 AA;  24295 MW;  0BC7DEF871177CD3 CRC64;
     MEQPYVYAYP QGSGPSGAPT PQAGGVVVDP KYCAPYPIDM AIVRKMMSLT DGNFVITDVN
     GNLLFKVKEP VFGLHDKRVL LDGSGTPVVT LREKMVSMHD RWQVFRGGST DQRDLLYTVK
     RSSMLQLKTK LDVFLGHNKD EKRCDFRVKG SWLERSCVVY AGESDAIVAQ MHRKHTVQSV
     FLGKDNFSVT VYPNVDYAFI ASLVVILDDV NREDRAA
//

If you have problems or comments...

PBIL Back to PBIL home page