(data stored in ACNUC1829 zone)

SWISSPROT: B0W4A5_CULQU

ID   B0W4A5_CULQU            Unreviewed;       248 AA.
AC   B0W4A5;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=6033041 {ECO:0000313|VectorBase:CPIJ002008-PA};
GN   ORFNames=CpipJ_CPIJ002008 {ECO:0000313|EMBL:EDS33190.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EMBL:EDS33190.1, ECO:0000313|VectorBase:CPIJ002008-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS33190.1,
RC   ECO:0000313|VectorBase:CPIJ002008-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ002008-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ002008-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS01169470}.
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DR   EMBL; DS231836; EDS33190.1; -; Genomic_DNA.
DR   RefSeq; XP_001843547.1; XM_001843495.1.
DR   STRING; 7176.CPIJ002008-PA; -.
DR   EnsemblMetazoa; CPIJ002008-RA; CPIJ002008-PA; CPIJ002008.
DR   GeneID; 6033041; -.
DR   KEGG; cqu:CpipJ_CPIJ002008; -.
DR   VectorBase; CPIJ002008-RA; CPIJ002008-PA; CPIJ002008.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   HOGENOM; HOG000230651; -.
DR   InParanoid; B0W4A5; -.
DR   OMA; YWASISE; -.
DR   OrthoDB; 1406905at2759; -.
DR   PhylomeDB; B0W4A5; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; SSF48652; 1.
PE   3: Inferred from homology;
DR   PRODOM; B0W4A5.
DR   SWISS-2DPAGE; B0W4A5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Membrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429796};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00028015};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429788}.
FT   TRANSMEM     12     37       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     57     77       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     89    109       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM    201    224       Helical. {ECO:0000256|RuleBase:RU361218}.
SQ   SEQUENCE   248 AA;  27491 MW;  A86D3A3AD846FB70 CRC64;
     MALGCTLTTV KFLLLVTNLF TLLCGVSLAI VGTVMHVRYS SINGLYAEQN SLLAYEALLA
     VTLGMIAFVI SFFGFFGAAR NSACMISTYA FLLLVLMVIQ IGFAAGSFLQ YEEARVYFLG
     RVEANFDRIF RSAGGADLRS NPAIARVQRL FQCCGKHSYK EWGRWLPESC CRGGITAGCK
     PYETGCVEQL EEYFVRSART FGWLLICFTV IEFVAALSGC WLANGLRDEE AARKRVRFQR
     VPAGRVNP
//

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