(data stored in ACNUC1829 zone)

SWISSPROT: B0WVX8_CULQU

ID   B0WVX8_CULQU            Unreviewed;       221 AA.
AC   B0WVX8;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   30-AUG-2017, entry version 62.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=6043970 {ECO:0000313|VectorBase:CPIJ011268-PA};
GN   ORFNames=CpipJ_CPIJ011268 {ECO:0000313|EMBL:EDS35810.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EMBL:EDS35810.1, ECO:0000313|VectorBase:CPIJ011268-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS35810.1,
RC   ECO:0000313|VectorBase:CPIJ011268-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ011268-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ011268-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS00545671}.
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DR   EMBL; DS232134; EDS35810.1; -; Genomic_DNA.
DR   RefSeq; XP_001861550.1; XM_001861515.1.
DR   UniGene; Cpi.6289; -.
DR   ProteinModelPortal; B0WVX8; -.
DR   EnsemblMetazoa; CPIJ011268-RA; CPIJ011268-PA; CPIJ011268.
DR   GeneID; 6043970; -.
DR   KEGG; cqu:CpipJ_CPIJ011268; -.
DR   VectorBase; CPIJ011268-RA; CPIJ011268-PA; CPIJ011268.
DR   eggNOG; KOG3882; Eukaryota.
DR   eggNOG; ENOG4111IRY; LUCA.
DR   HOGENOM; HOG000230651; -.
DR   InParanoid; B0WVX8; -.
DR   KO; K06497; -.
DR   OMA; KCCGRSG; -.
DR   OrthoDB; EOG091G12WV; -.
DR   PhylomeDB; B0WVX8; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000301; Tetraspanin.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; SSF48652; 1.
PE   3: Inferred from homology;
DR   PRODOM; B0WVX8.
DR   SWISS-2DPAGE; B0WVX8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Membrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00027997};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00429797};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218,
KW   ECO:0000256|SAAS:SAAS00028005}.
FT   TRANSMEM     14     33       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     45     71       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM     83    103       Helical. {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM    186    209       Helical. {ECO:0000256|RuleBase:RU361218}.
SQ   SEQUENCE   221 AA;  23739 MW;  C090ECD213990A48 CRC64;
     MCVTCPAGFR LRNVVFLCGI ALVVIGGVSL AKISDLQQIS EDHNIVAPSI FFIILGSVVF
     VIAFFGCCGA IRESYCMTQT YGFFLLILII GQIVIAALVF IYVGDVREAF KTGFAKIFAE
     RDRQTNAELI DTIQSNLQCC GKSSALDWLG NTPQSCCQSG TAPLCVPWLR GCTSALGEFI
     DTTGVVLGWV SLGVAVVELV GLISACCLAN GIRNRDRRSG Y
//

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