(data stored in ACNUC31183 zone)

SWISSPROT: B0XEZ4_CULQU

ID   B0XEZ4_CULQU            Unreviewed;       862 AA.
AC   B0XEZ4;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   30-AUG-2017, entry version 51.
DE   SubName: Full=Rap GTPase-activating protein {ECO:0000313|EMBL:EDS26342.1, ECO:0000313|VectorBase:CPIJ018142-PA};
GN   Name=6051858 {ECO:0000313|VectorBase:CPIJ018142-PA};
GN   ORFNames=CpipJ_CPIJ018142 {ECO:0000313|EMBL:EDS26342.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EMBL:EDS26342.1, ECO:0000313|VectorBase:CPIJ018142-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS26342.1,
RC   ECO:0000313|VectorBase:CPIJ018142-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ018142-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ018142-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; DS232884; EDS26342.1; -; Genomic_DNA.
DR   RefSeq; XP_001868216.1; XM_001868181.1.
DR   UniGene; Cpi.11529; -.
DR   ProteinModelPortal; B0XEZ4; -.
DR   STRING; 7176.CPIJ018142-PA; -.
DR   EnsemblMetazoa; CPIJ018142-RA; CPIJ018142-PA; CPIJ018142.
DR   GeneID; 6051858; -.
DR   KEGG; cqu:CpipJ_CPIJ018142; -.
DR   VectorBase; CPIJ018142-RA; CPIJ018142-PA; CPIJ018142.
DR   eggNOG; KOG3686; Eukaryota.
DR   eggNOG; ENOG410XTIX; LUCA.
DR   HOGENOM; HOG000231640; -.
DR   InParanoid; B0XEZ4; -.
DR   KO; K17700; -.
DR   OMA; VANQEHM; -.
DR   OrthoDB; EOG091G028T; -.
DR   PhylomeDB; B0XEZ4; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR000331; Rap_GAP_dom.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; SSF111347; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
DR   PRODOM; B0XEZ4.
DR   SWISS-2DPAGE; B0XEZ4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN      272    488       Rap-GAP. {ECO:0000259|PROSITE:PS50085}.
SQ   SEQUENCE   862 AA;  92990 MW;  7F83A5EAFE69C7DF CRC64;
     MFERAFFPPR DLCAKSSREE RISNPHGSSN NGGNNNDASN NLTVQIPQQT RSLLRHSNSM
     SSNPHSNSSS TPASPHLLSN SSSGHLHHTL SNGGSLHHHS SQYQSQSSVS SQSSSIISAV
     PPLQRLLEDH LSKPAPYQMI VIPNSGGYWI DGTDHDAGYD IPSHATWRVG KIESDDTAKC
     YRRFFISREH SNLVGHDDQL GPVLLSIKSE NVANQDHIRI LLRLRTGTMH EIIPASCLGS
     NPSPIKMARL LNDQINVDSF MPVLCPKAST LIASYDEHVL VTNFKFGVLY QRYGQTTEEE
     LFCNSDTTPA LEEFLDLLGQ RIRLRDHKGY RGGLDIQNGH TGDTAVYEVF KEREIMFHVS
     TLLPYTEGDP QQLQRKRHIG NDIVAIVFQE ENTPFSPAMI ASHFLHAFIV VQPLEPNTPN
     CRYKISVTAR DDVPFFGPTL PQPSVFKKGP ELKEFLLTKL INAENACYKA DKFAQLELRT
     RTSLLQNLVD ELKEKTRDFL GADLLGAPTS PTPETPKSEG GFTGSRFIDT VKKALNARLR
     SQNSDPTNGV DSTNPKHHNS IKKSKEVSEA PCGPTGQNVN IGRSLSKSST TGSRKSPNDS
     VASSPDITSR CSLNPGGTLN NNNTNTANNN HHGGSGHHAG AHGPKGGSGN NNNNNNGPVA
     MSETSDDSSL NSVDLDPMDA GATYIDSDTG LESMSSADAT TKACSLCLDG VDRAERSTNG
     GGSVISVSVG TGSTGGDSTR DLRSSTGSSS GGVVVGATTT TTSVTGGGGG GHGSVTVITS
     QGAVVVGPEI VQQMDGYKQE ITRLKCDKLD LLRQNVTCQR DIKRLREREL SLQGDLAAAG
     KEILRLRDLL KEYMPATAGE PI
//

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