(data stored in SCRATCH zone)

SWISSPROT: B1K3Q8_BURCC

ID   B1K3Q8_BURCC            Unreviewed;       528 AA.
AC   B1K3Q8;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACA92779.1};
GN   OrderedLocusNames=Bcenmc03_3627 {ECO:0000313|EMBL:ACA92779.1};
OS   Burkholderia cenocepacia (strain MC0-3).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=406425 {ECO:0000313|EMBL:ACA92779.1, ECO:0000313|Proteomes:UP000002169};
RN   [1] {ECO:0000313|Proteomes:UP000002169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC0-3 {ECO:0000313|Proteomes:UP000002169};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-
RT   3.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP000959; ACA92779.1; -; Genomic_DNA.
DR   RefSeq; WP_011548131.1; NC_010515.1.
DR   EnsemblBacteria; ACA92779; ACA92779; Bcenmc03_3627.
DR   KEGG; bcm:Bcenmc03_3627; -.
DR   HOGENOM; HOG000112189; -.
DR   KO; K03446; -.
DR   OMA; NGAWIST; -.
DR   BioCyc; BCEN406425:G1GBC-3851-MONOMER; -.
DR   Proteomes; UP000002169; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1K3Q8.
DR   SWISS-2DPAGE; B1K3Q8.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002169};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     22     41       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     62     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     87    108       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    163       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    175    196       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    208    230       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    242    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    280    301       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    316    334       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    346    366       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    498    515       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       24    520       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   528 AA;  56728 MW;  547DCBCF6D1771B7 CRC64;
     MADTPATIPL PPHEGRASVT DWIAVAAGAL GALMATLDIS ITNSALPQIQ GEIGATGTEG
     TWISTGYLMS EIVMIPLAAW LTRVFGLRNF LLTNSALFIA FSMMCGWSHS LPMMIAGRIG
     QGFTGGALIP TAQTIIRTRL PLSQLPVGMT LFGLIVLLGP LFGPVLGGWL AENVNWSWCF
     FLNLPVCLLL MALLVFGLPS DRPQWSAFFN ADWLGILGLA IGLSSLTVVL EEGQRERWFE
     SQMIVTLSIV SFIGMVLIAL SQRFAKRPIM RLSLMRNPRY ASVIVIVSAV GAGLYGVSYL
     LPQFLAIVAG YNAEQAGAIM LLSGLPAFLV MPILPRLLGK VDFRILVITG LLLFCLSCML
     DISLTAQSVG HDFVWSQLIR GLAQMLAMMP LNQASMAAVA REDSGDAAGL YNMARNLGGS
     IGLAIIGTVI DRRTTFHTAA LRESVTANSL IGQDRLSAYA ANWFAHTGDL AYSNLRALGQ
     LAQQIQIQAV VMTYSETFYL LGLALLACVP LALLLRTPRG PQPMSSGH
//

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