(data stored in SCRATCH zone)

SWISSPROT: B1K4Z7_BURCC

ID   B1K4Z7_BURCC            Unreviewed;       524 AA.
AC   B1K4Z7;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACA92921.1};
GN   OrderedLocusNames=Bcenmc03_3769 {ECO:0000313|EMBL:ACA92921.1};
OS   Burkholderia cenocepacia (strain MC0-3).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=406425 {ECO:0000313|EMBL:ACA92921.1, ECO:0000313|Proteomes:UP000002169};
RN   [1] {ECO:0000313|Proteomes:UP000002169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC0-3 {ECO:0000313|Proteomes:UP000002169};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-
RT   3.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP000959; ACA92921.1; -; Genomic_DNA.
DR   RefSeq; WP_012338532.1; NC_010515.1.
DR   EnsemblBacteria; ACA92921; ACA92921; Bcenmc03_3769.
DR   KEGG; bcm:Bcenmc03_3769; -.
DR   HOGENOM; HOG000112189; -.
DR   KO; K03446; -.
DR   OMA; GNKKGWL; -.
DR   BioCyc; BCEN406425:G1GBC-4001-MONOMER; -.
DR   Proteomes; UP000002169; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1K4Z7.
DR   SWISS-2DPAGE; B1K4Z7.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002169};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     18     38       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     58     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    105       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    111    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    166       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    172    195       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    207    226       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    238    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    281    304       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    310    333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    358       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    407    426       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    493    510       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       20    516       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   524 AA;  56534 MW;  54AF15611EAA4C78 CRC64;
     MTTAFSGDPA SQPTKQRVFA FALMCVGFFM ATLDIQIVAS SLRDIGGGLS ASQDELSWVQ
     TAYLIAEIIV IPMSGWLSKV MSTRWLFAAS AVGFTITSML CGLAWDINSM ILFRGLQGAL
     GAAMIPTVFT TAFVLFPGRQ RLIASTTIGA LASLAPAIGP VIGGWITDQW SWHWLFYLNL
     VPGIAVAALV PRYVHIDAPD LSLIKRGDYL GIALMSGFLG CLEYVLEEGP RKNWFGDDAI
     VICAWISGIC GFLFIVHALT AKDPIVDLRA LAVRNFGIGS LLSFVTGIGI FVTVFLTPLF
     LAQVRAFSSL QIGIALLSVG AFQLIALCAY AFAARYVSMR ALLVFGLICF GLGCYLYTPI
     THDWGWQELL LPQALRGIGQ QFSVPPIVTM ALGSLPQSRL KSASGLFNLM RNLGGAIGIA
     VSATMLNDRL NFHYLRLNEH VSAGEPQVAS LLDRQAEYWG SVAGNTLNTA QAGLANLHRL
     IYREALTLTY ADAYYALSLC FVVALLAVVF SKPITLNAPP PDAH
//

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