(data stored in SCRATCH zone)

SWISSPROT: B1VM02_STRGG

ID   B1VM02_STRGG            Unreviewed;       252 AA.
AC   B1VM02;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   05-JUL-2017, entry version 56.
DE   SubName: Full=Putative RNA polymerase ECF-subfamily sigma factor {ECO:0000313|EMBL:BAG16903.1};
GN   OrderedLocusNames=SGR_7065t {ECO:0000313|EMBL:BAG23892.1}, SGR_74t
GN   {ECO:0000313|EMBL:BAG16903.1};
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=455632 {ECO:0000313|EMBL:BAG16903.1, ECO:0000313|Proteomes:UP000001685};
RN   [1] {ECO:0000313|EMBL:BAG16903.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / NBRC 13350 {ECO:0000313|Proteomes:UP000001685}, and
RC   NBRC 13350 {ECO:0000313|EMBL:BAG16903.1};
RX   PubMed=18375553; DOI=10.1128/JB.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism
RT   Streptomyces griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
RN   [2] {ECO:0000313|EMBL:BAG16903.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 13350 {ECO:0000313|EMBL:BAG16903.1};
RX   PubMed=18364359; DOI=10.1074/jbc.M710461200;
RA   Funabashi M., Funa N., Horinouchi S.;
RT   "Phenolic lipids synthesized by type III polyketide synthase confer
RT   penicillin resistance on Streptomyces griseus.";
RL   J. Biol. Chem. 283:13983-13991(2008).
RN   [3] {ECO:0000313|EMBL:BAG16903.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 13350 {ECO:0000313|EMBL:BAG16903.1};
RA   Hirano S., Tanaka K., Ohnishi Y., Horinouchi S.;
RT   "Conditionally positive effect of the TetR-family transcriptional
RT   regulator AtrA on streptomycin production by Streptomyces griseus.";
RL   Microbiology (Mosc.) 154:905-914(2008).
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|SAAS:SAAS00565917}.
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DR   EMBL; AP009493; BAG16903.1; -; Genomic_DNA.
DR   EMBL; AP009493; BAG23892.1; -; Genomic_DNA.
DR   RefSeq; WP_012377490.1; NC_010572.1.
DR   ProteinModelPortal; B1VM02; -.
DR   STRING; 455632.SGR_7065t; -.
DR   EnsemblBacteria; BAG16903; BAG16903; SGR_74t.
DR   EnsemblBacteria; BAG23892; BAG23892; SGR_7065t.
DR   GeneID; 6213954; -.
DR   KEGG; sgr:SGR_7065t; -.
DR   KEGG; sgr:SGR_74t; -.
DR   KO; K03088; -.
DR   Proteomes; UP000001685; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3_r4.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1VM02.
DR   SWISS-2DPAGE; B1VM02.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001685};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00611263};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001685};
KW   Sigma factor {ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00611294};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    212       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    218    237       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       21     69       Sigma70_r2. {ECO:0000259|Pfam:PF04542}.
FT   DOMAIN      110    162       Sigma70_r4_2. {ECO:0000259|Pfam:PF08281}.
SQ   SEQUENCE   252 AA;  27740 MW;  EEDDE1EEF2B6BF85 CRC64;
     MTFERAYELY YRPLILSVRQ RGRAWGLSEQ DVDVEALVQD TFEQALNDWD NIRVPRAWLY
     TVARRRLARC ISTAALRADG DPADHTEQGT VGWSSLAPSA STQDLVAARE IVELIQLMPQ
     PRRQEVAYLR YIEGWGFNEI AEQLGCCPAT ARVHALNARA HLVTNCSGSS IYIAGRDMHI
     ASNGSGSASG SGSGWLVALL VLGCVLATGI LVGWSWVLAA AGGVAAVALT GWGWNAWRAR
     QHDSRQEHRR LR
//

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