(data stored in SCRATCH zone)

SWISSPROT: B2JKY3_PARP8

ID   B2JKY3_PARP8            Unreviewed;       505 AA.
AC   B2JKY3;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACC72512.1};
GN   OrderedLocusNames=Bphy_3357 {ECO:0000313|EMBL:ACC72512.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC72512.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A.,
RA   Melkonian R., James E.K., Young J.P., Bena G., Hauser L., Land M.,
RA   Kyrpides N., Bruce D., Chain P., Copeland A., Pitluck S., Woyke T.,
RA   Lizotte-Waniewski M., Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad
RT   host range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001044; ACC72512.1; -; Genomic_DNA.
DR   RefSeq; WP_012402685.1; NC_010623.1.
DR   EnsemblBacteria; ACC72512; ACC72512; Bphy_3357.
DR   GeneID; 27743042; -.
DR   KEGG; bph:Bphy_3357; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239126; -.
DR   OMA; WCILAFG; -.
DR   OrthoDB; 1558246at2; -.
DR   BioCyc; BPHY391038:G1GBS-3453-MONOMER; -.
DR   Proteomes; UP000001192; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2JKY3.
DR   SWISS-2DPAGE; B2JKY3.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001192};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     25     48       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     79       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     91    110       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    116    137       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    149    167       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    211    230       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    242    259       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    279    303       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    315    334       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    346    367       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    373    395       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    407    430       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    471    497       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    502       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   505 AA;  53750 MW;  CD9081D547D7BB46 CRC64;
     MESPTSTANM ADAMPATIER PSLRVLFPAL LLVMLLAALD QTIVSTALPT IVGELGGLDS
     LSWVVTAYLL TSTIVVPLYG KFGDLFGRKI VLQTAIVLFL IGSALCGVAQ NMTQLILLRA
     LQGLGGGGLL VITMAAIGDV IPPAERGRYQ GVFGGVFGLA TVIGPMMGGF IVDHLSWRWI
     FYINVPLGIA ALLVIGAVFK PRVQQVKHTI DYMGAAFLAG ALTCVILFTS QGGTVLAWTS
     PQLWGTLLLA FICIGGFVYE ERLAAEPIMP LELFRDRTFL LSSAIGFIVG VSLFGSVTFL
     PMYLQVVKNS TPSQAGMQML PMMGGVMLMS IVTGRLISRI GKYRMFPIMG TFLVGIAMLL
     LTTLKLTTSV QVMYAYMAVL GCGLGMVMQV LILAVQNAVP FKHLGTATSG ATLFRSIGGS
     VGVAAFGAIF SNGLSARLQA LIPPDTELPH ALGPAAIHHL PAMLRDDYLQ AFAGALHTVY
     IVAACVVVLA FALAWLLRDH PLRHH
//

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