(data stored in SCRATCH zone)

SWISSPROT: B2JMJ9_PARP8

ID   B2JMJ9_PARP8            Unreviewed;       792 AA.
AC   B2JMJ9;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442};
DE            EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442};
GN   OrderedLocusNames=Bphy_3658 {ECO:0000313|EMBL:ACC72793.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC72793.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A.,
RA   Melkonian R., James E.K., Young J.P., Bena G., Hauser L., Land M.,
RA   Kyrpides N., Bruce D., Chain P., Copeland A., Pitluck S., Woyke T.,
RA   Lizotte-Waniewski M., Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad
RT   host range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-
CC         COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC       {ECO:0000256|RuleBase:RU000442}.
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DR   EMBL; CP001044; ACC72793.1; -; Genomic_DNA.
DR   RefSeq; WP_012402966.1; NC_010623.1.
DR   STRING; 391038.Bphy_3658; -.
DR   EnsemblBacteria; ACC72793; ACC72793; Bphy_3658.
DR   GeneID; 27743326; -.
DR   KEGG; bph:Bphy_3658; -.
DR   eggNOG; ENOG4105CQ2; Bacteria.
DR   eggNOG; COG0417; LUCA.
DR   HOGENOM; HOG000221829; -.
DR   KO; K02336; -.
DR   OMA; AFTHLYM; -.
DR   OrthoDB; 261704at2; -.
DR   BioCyc; BPHY391038:G1GBS-3754-MONOMER; -.
DR   Proteomes; UP000001192; Chromosome 2.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 2.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF00136; DNA_pol_B; 2.
DR   Pfam; PF03104; DNA_pol_B_exo1; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2JMJ9.
DR   SWISS-2DPAGE; B2JMJ9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001192};
KW   DNA replication {ECO:0000256|RuleBase:RU000442};
KW   DNA-binding {ECO:0000256|RuleBase:RU000442};
KW   DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442,
KW   ECO:0000313|EMBL:ACC72793.1};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442,
KW   ECO:0000313|EMBL:ACC72793.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW   Transferase {ECO:0000256|RuleBase:RU000442,
KW   ECO:0000313|EMBL:ACC72793.1}.
FT   DOMAIN      204    302       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      385    437       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN      496    747       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
SQ   SEQUENCE   792 AA;  90230 MW;  DB536B0E594714F0 CRC64;
     MNELEQGFLL TRHWRDTGTE TEVEFWLATD DGPRHIRLRP QPNVAFVPAA QRPRADEVLR
     QEKSTRGVEL RPLDLRDFQH RPVLGLYCPQ YRQLIGLEKR LKQGGVDVYE ADVFPPDRYM
     MERFITAPVL FRGEANPIGG PLLNGDMKPA TGYRPKLRLV SLDIETSAQA ELYSIALEGC
     GQRQVYMLGP ENGDASGLDF ALEYCETRAQ LIERLVEWLE RHDPDAIIGW NVVQFDLKVL
     HETAQRYGVP LRIGRGGAVL EWREHGLKQN HFFAGAAGRL IIDGIEALRS ATWSFPSFSL
     EYVAQSVLGE GKSIDNPYQR MEEIQRRFDE DKPALARYNL KDCELVTRVF AKTDLLSFLL
     ERATVTGLPA DRSGGSVAAF THLYMPRMHR LGFVAPNLGD VAGAASPGGF VMDSKPGLYD
     SVLVLDYKSL YPSIIRSFLI DPVGLIDGLR HPDDADSVPG FLGARFSRAQ HCLPSIVAQV
     WEGREAAKRE QNKPLSQALK IIMNAFYGVL GSTGCRFFDP RLASSITMRG HEIMHRTREL
     IEASGYTVIY GDTDSTFVWL KHAHDEQDAV RIGRELVGAI NAWWREHLRE RFDLESALEL
     QFERHYRRFF MPTVRGAEEG SKKRYAGLTV MADGSEEVVY KGLETVRTDW TPLAQRFQQE
     LYLRIFKQQP YRDYVRDYVR RTLAGEFDDL LVYRKRLRRP LSDYERNVPP HVRAARSADE
     FNRQRGRPLQ YQNGGWISYV MTGSGPEPLE TLRSPIDHEH YLTKQLQPVA DAILPLLKDD
     FVTLAAGQAQ LF
//

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