(data stored in SCRATCH zone)

SWISSPROT: B2JMN1_PARP8

ID   B2JMN1_PARP8            Unreviewed;       664 AA.
AC   B2JMN1;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   08-MAY-2019, entry version 82.
DE   RecName: Full=RNA polymerase sigma factor RpoD {ECO:0000256|HAMAP-Rule:MF_00963};
DE   AltName: Full=Sigma-70 {ECO:0000256|HAMAP-Rule:MF_00963};
GN   Name=rpoD {ECO:0000256|HAMAP-Rule:MF_00963};
GN   OrderedLocusNames=Bphy_3690 {ECO:0000313|EMBL:ACC72825.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC72825.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A.,
RA   Melkonian R., James E.K., Young J.P., Bena G., Hauser L., Land M.,
RA   Kyrpides N., Bruce D., Chain P., Copeland A., Pitluck S., Woyke T.,
RA   Lizotte-Waniewski M., Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad
RT   host range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor is the primary sigma factor
CC       during exponential growth. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00535554}.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic
CC       core. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003340}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003349}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoD/SigA
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00535555}.
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DR   EMBL; CP001044; ACC72825.1; -; Genomic_DNA.
DR   RefSeq; WP_012402998.1; NC_010623.1.
DR   STRING; 391038.Bphy_3690; -.
DR   EnsemblBacteria; ACC72825; ACC72825; Bphy_3690.
DR   GeneID; 27743355; -.
DR   KEGG; bph:Bphy_3690; -.
DR   eggNOG; ENOG4105DG1; Bacteria.
DR   eggNOG; COG0568; LUCA.
DR   HOGENOM; HOG000270272; -.
DR   KO; K03086; -.
DR   OMA; QIEDTMA; -.
DR   OrthoDB; 1565734at2; -.
DR   BioCyc; BPHY391038:G1GBS-3785-MONOMER; -.
DR   Proteomes; UP000001192; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_00963; Sigma70_RpoD_SigA; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR007631; RNA_pol_sigma_70_non-ess.
DR   InterPro; IPR007127; RNA_pol_sigma_70_r1_1.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012760; RNA_pol_sigma_RpoD_C.
DR   InterPro; IPR028630; Sigma70_RpoD.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04546; Sigma70_ner; 1.
DR   Pfam; PF03979; Sigma70_r1_1; 1.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02393; RpoD_Cterm; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2JMN1.
DR   SWISS-2DPAGE; B2JMN1.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001192};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00003326};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN      453    466       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      622    648       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    623    642       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00963}.
FT   REGION      429    499       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      508    584       Sigma-70 factor domain-3.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      597    650       Sigma-70 factor domain-4.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   COILED      408    435       {ECO:0000256|SAM:Coils}.
FT   MOTIF       453    456       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00963}.
SQ   SEQUENCE   664 AA;  73613 MW;  764749300EEECA88 CRC64;
     MAKLDRDNSQ FETTAAKTPK RAAKAKAQPA APQDSALMES LAEERQRQMR ALIALGRERG
     YLTHADINDH LPDNFTETAA METIVSTFGE MGVSVYETAP DAETLLLNDG PSAAASDDQA
     DEEAEVALST VDSEFGRTTD PVRMYMREMG ASELLTRAGE IEIAKRIEGG LQDMVQAIAM
     CPSIIATILA DVDRVVAGEI RIDELVDGIS DTTEAAELDD DSAEAAAEEE LETSASDDDS
     DDEDGDLSDD GGEKANAARL EQLTADSLAI FERVRALFAS VPDMPVTDKR RATAIANLRE
     SIQQELTPIR FTAKTIDRLC AEVQAQVAQV RAIERSILQI AVDRCDMPRE TFVESFPGNE
     TDLDWTMRVA AKSKTYGPAL ERHLPAIQSE QQKLVDIEAS IALPLQQLKQ INKQLGSAES
     KMRQAKREMI EANLRLVISI AKKYVNRGMH FLDLIQEGNI GLMKAVDKFE YRRGWKFSTY
     ATWWVRQAIT RAIADQARTI RVPVHMIESI NKLNRIQREI VQQTGQEPHP SVLAERMDMP
     EAKIRSILKI AKNPASLDSP VGEDADTTLG DMIEDTSATS PADAAVHANM RRAIDEALDA
     LTPREAKVLR MRYGIDTASE LTLEEVGRQF DVTRERIRQI EGKAIRKLNH PSRADKLRPF
     LERS
//

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