(data stored in SCRATCH zone)

SWISSPROT: B2TE74_PARPJ

ID   B2TE74_PARPJ            Unreviewed;       315 AA.
AC   B2TE74;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 71.
DE   RecName: Full=Beta-lactamase {ECO:0000256|RuleBase:RU361140, ECO:0000256|SAAS:SAAS00063099};
DE            EC=3.5.2.6 {ECO:0000256|RuleBase:RU361140, ECO:0000256|SAAS:SAAS00063099};
DE   Flags: Precursor;
GN   OrderedLocusNames=Bphyt_4009 {ECO:0000313|EMBL:ACD18395.1};
OS   Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)
OS   (Burkholderia phytofirmans).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=398527 {ECO:0000313|EMBL:ACD18395.1, ECO:0000313|Proteomes:UP000001739};
RN   [1] {ECO:0000313|EMBL:ACD18395.1, ECO:0000313|Proteomes:UP000001739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17436 / LMG 22146 / PsJN
RC   {ECO:0000313|Proteomes:UP000001739};
RX   PubMed=21551308; DOI=10.1128/JB.05055-11;
RA   Weilharter A., Mitter B., Shin M.V., Chain P.S., Nowak J.,
RA   Sessitsch A.;
RT   "Complete genome sequence of the plant growth-promoting endophyte
RT   Burkholderia phytofirmans strain PsJN.";
RL   J. Bacteriol. 193:3383-3384(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC         Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC         ChEBI:CHEBI:140347; EC=3.5.2.6;
CC         Evidence={ECO:0000256|RuleBase:RU361140,
CC         ECO:0000256|SAAS:SAAS01122538};
CC   -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC       {ECO:0000256|RuleBase:RU361140, ECO:0000256|SAAS:SAAS00559532}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001053; ACD18395.1; -; Genomic_DNA.
DR   RefSeq; WP_012425911.1; NC_010676.1.
DR   STRING; 398527.Bphyt_4009; -.
DR   MEROPS; S11.A01; -.
DR   EnsemblBacteria; ACD18395; ACD18395; Bphyt_4009.
DR   KEGG; bpy:Bphyt_4009; -.
DR   eggNOG; ENOG4108J4B; Bacteria.
DR   eggNOG; COG2367; LUCA.
DR   HOGENOM; HOG000201073; -.
DR   KO; K17836; -.
DR   OMA; EWMKGNA; -.
DR   OrthoDB; 991474at2; -.
DR   BioCyc; BPHY398527:GJEX-4008-MONOMER; -.
DR   Proteomes; UP000001739; Chromosome 2.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-UniRule.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   InterPro; IPR023650; Beta-lactam_class-A_AS.
DR   PRINTS; PR00118; BLACTAMASEA.
DR   SUPFAM; SSF56601; SSF56601; 1.
DR   PROSITE; PS00146; BETA_LACTAMASE_A; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2TE74.
DR   SWISS-2DPAGE; B2TE74.
KW   Antibiotic resistance {ECO:0000256|RuleBase:RU361140,
KW   ECO:0000256|SAAS:SAAS00129359};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001739};
KW   Hydrolase {ECO:0000256|RuleBase:RU361140,
KW   ECO:0000256|SAAS:SAAS00129356, ECO:0000313|EMBL:ACD18395.1}.
SQ   SEQUENCE   315 AA;  32545 MW;  A2BC5F784030BA45 CRC64;
     MITRRKFAGA MLGVSIAGVA VGSVGAFGKA SGKTVKTGAA AQGRELAKAD AIRRRLAEIE
     AASGGRLGVS IVDTMSGVHA GLRTDERFPM CSTFKILVAG AVLARTDRGE ESLQRRVVFS
     LSDVVSNSPA TSKHTRELIG NAGMSVAELC KAAITLSDNT AANLLLSTFG GPAGLTAFAR
     SLGDRVTRLD RIEPALNEGT PGDLRDTTTP NAMLGNLREL LLGERLSSSS RAQLLAWLAA
     NETGGARIRA KLPKDWGVGD KTGTGDHGTA NDVAILWPPG RGPVLVTVYL TETDGDAARS
     NTAIADVGAL VVASI
//

If you have problems or comments...

PBIL Back to PBIL home page