(data stored in SCRATCH zone)

SWISSPROT: B2TEG6_PARPJ

ID   B2TEG6_PARPJ            Unreviewed;       305 AA.
AC   B2TEG6;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Probable 5-dehydro-4-deoxyglucarate dehydratase {ECO:0000256|HAMAP-Rule:MF_00694};
DE            EC=4.2.1.41 {ECO:0000256|HAMAP-Rule:MF_00694};
DE   AltName: Full=5-keto-4-deoxy-glucarate dehydratase {ECO:0000256|HAMAP-Rule:MF_00694};
DE            Short=KDGDH {ECO:0000256|HAMAP-Rule:MF_00694};
GN   OrderedLocusNames=Bphyt_4103 {ECO:0000313|EMBL:ACD18487.1};
OS   Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)
OS   (Burkholderia phytofirmans).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=398527 {ECO:0000313|EMBL:ACD18487.1, ECO:0000313|Proteomes:UP000001739};
RN   [1] {ECO:0000313|EMBL:ACD18487.1, ECO:0000313|Proteomes:UP000001739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17436 / LMG 22146 / PsJN
RC   {ECO:0000313|Proteomes:UP000001739};
RX   PubMed=21551308; DOI=10.1128/JB.05055-11;
RA   Weilharter A., Mitter B., Shin M.V., Chain P.S., Nowak J.,
RA   Sessitsch A.;
RT   "Complete genome sequence of the plant growth-promoting endophyte
RT   Burkholderia phytofirmans strain PsJN.";
RL   J. Bacteriol. 193:3383-3384(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-
CC         dioxopentanoate + CO2 + H2O; Xref=Rhea:RHEA:24608,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:42819, ChEBI:CHEBI:58136; EC=4.2.1.41;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00694,
CC         ECO:0000256|SAAS:SAAS01120014};
CC   -!- PATHWAY: Carbohydrate acid metabolism; D-glucarate degradation;
CC       2,5-dioxopentanoate from D-glucarate: step 2/2.
CC       {ECO:0000256|HAMAP-Rule:MF_00694, ECO:0000256|SAAS:SAAS00548743}.
CC   -!- SIMILARITY: Belongs to the DapA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00694, ECO:0000256|PIRNR:PIRNR001365,
CC       ECO:0000256|SAAS:SAAS00579284}.
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DR   EMBL; CP001053; ACD18487.1; -; Genomic_DNA.
DR   RefSeq; WP_012426003.1; NC_010676.1.
DR   STRING; 398527.Bphyt_4103; -.
DR   EnsemblBacteria; ACD18487; ACD18487; Bphyt_4103.
DR   KEGG; bpy:Bphyt_4103; -.
DR   eggNOG; ENOG4105UVJ; Bacteria.
DR   eggNOG; COG0329; LUCA.
DR   HOGENOM; HOG000173605; -.
DR   KO; K01707; -.
DR   OMA; RNRKKGY; -.
DR   OrthoDB; 1438588at2; -.
DR   BioCyc; BPHY398527:GJEX-4101-MONOMER; -.
DR   UniPathway; UPA00564; UER00628.
DR   Proteomes; UP000001739; Chromosome 2.
DR   GO; GO:0047448; F:5-dehydro-4-deoxyglucarate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042838; P:D-glucarate catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00951; KDGDH; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00694; KDGDH; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   InterPro; IPR017655; Dehydro-deoxyglucarate_dehyd.
DR   PANTHER; PTHR12128; PTHR12128; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   SMART; SM01130; DHDPS; 1.
DR   TIGRFAMs; TIGR03249; KdgD; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2TEG6.
DR   SWISS-2DPAGE; B2TEG6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001739};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00694, ECO:0000256|PIRNR:PIRNR001365,
KW   ECO:0000256|SAAS:SAAS00579236}.
SQ   SEQUENCE   305 AA;  32852 MW;  CB7FA7119399028C CRC64;
     MTSPQELKAI VSEGLLSFPV TDFDAHGEFR ADTYAARLEW LAPYGATALF AAGGTGEFFS
     LTKTDYTNVI RTATDTCRGK VPILAGAGGP TRVAIEYAQE AERLGASGVL LMPHYLTEAS
     QEGIAAHVEQ VCKSVPNIGV IVYNRANSKL NADMLERLAD RCPNLIGFKD GVGEIEAMVT
     IRRRLGERFS YLGGLPTAEV YAAAYKALGV PVYSSAVFNF IPKTAMEFYR AVAANDHATQ
     GRLLDEFFLP YLAIRNRRAG YAVSIVKAGA KLVGHDAGPV RAPLTDLTDE ESAQLDALIR
     KLGAQ
//

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