(data stored in SCRATCH zone)

SWISSPROT: B2TEU4_PARPJ

ID   B2TEU4_PARPJ            Unreviewed;       276 AA.
AC   B2TEU4;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   RecName: Full=S-formylglutathione hydrolase {ECO:0000256|RuleBase:RU363068};
DE            EC=3.1.2.12 {ECO:0000256|RuleBase:RU363068};
GN   OrderedLocusNames=Bphyt_4239 {ECO:0000313|EMBL:ACD18619.1};
OS   Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)
OS   (Burkholderia phytofirmans).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=398527 {ECO:0000313|EMBL:ACD18619.1, ECO:0000313|Proteomes:UP000001739};
RN   [1] {ECO:0000313|EMBL:ACD18619.1, ECO:0000313|Proteomes:UP000001739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17436 / LMG 22146 / PsJN
RC   {ECO:0000313|Proteomes:UP000001739};
RX   PubMed=21551308; DOI=10.1128/JB.05055-11;
RA   Weilharter A., Mitter B., Shin M.V., Chain P.S., Nowak J.,
RA   Sessitsch A.;
RT   "Complete genome sequence of the plant growth-promoting endophyte
RT   Burkholderia phytofirmans strain PsJN.";
RL   J. Bacteriol. 193:3383-3384(2011).
CC   -!- FUNCTION: Serine hydrolase involved in the detoxification of
CC       formaldehyde. {ECO:0000256|RuleBase:RU363068}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + S-formylglutathione = formate + glutathione + H(+);
CC         Xref=Rhea:RHEA:14961, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:15740, ChEBI:CHEBI:57688, ChEBI:CHEBI:57925;
CC         EC=3.1.2.12; Evidence={ECO:0000256|RuleBase:RU363068};
CC   -!- SIMILARITY: Belongs to the esterase D family.
CC       {ECO:0000256|RuleBase:RU363068}.
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DR   EMBL; CP001053; ACD18619.1; -; Genomic_DNA.
DR   RefSeq; WP_012426135.1; NC_010676.1.
DR   STRING; 398527.Bphyt_4239; -.
DR   ESTHER; burpp-b2teu4; A85-EsteraseD-FGH.
DR   MEROPS; S09.A38; -.
DR   EnsemblBacteria; ACD18619; ACD18619; Bphyt_4239.
DR   KEGG; bpy:Bphyt_4239; -.
DR   eggNOG; ENOG4105C4W; Bacteria.
DR   eggNOG; COG0627; LUCA.
DR   HOGENOM; HOG000263929; -.
DR   KO; K01070; -.
DR   OMA; WAPHYRM; -.
DR   OrthoDB; 1828423at2; -.
DR   BioCyc; BPHY398527:GJEX-4233-MONOMER; -.
DR   Proteomes; UP000001739; Chromosome 2.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0018738; F:S-formylglutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046294; P:formaldehyde catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000801; Esterase_put.
DR   InterPro; IPR014186; S-formylglutathione_hydrol.
DR   PANTHER; PTHR10061; PTHR10061; 1.
DR   Pfam; PF00756; Esterase; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   TIGRFAMs; TIGR02821; fghA_ester_D; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2TEU4.
DR   SWISS-2DPAGE; B2TEU4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001739};
KW   Hydrolase {ECO:0000256|RuleBase:RU363068,
KW   ECO:0000313|EMBL:ACD18619.1};
KW   Serine esterase {ECO:0000256|RuleBase:RU363068}.
SQ   SEQUENCE   276 AA;  30695 MW;  19D08CD7876374CD CRC64;
     MERIEQHASY GGYQEVWKHA SSTLGCEMRF GLYLPNAALR GQKCPVLYWL SGLTCTEQNF
     ITKAGAQRYA AEHGLIIVAP DTSPRGDDVP DDPGYDLGKG ASFYINAAQE PWATHYRMYD
     YVVDELPALV EAEFPANGAR AISGHSMGGH GALTIALRNP GRYRSVSAFS PIVAPTEVPW
     GRKAFRAYLG EDREVWKQYD TVELLKSAVE RLPLLVDQGE GDEFLEEQLK PQLLRAACEA
     AAHPLRLNLR PGYDHSYYFI SNFIGEHIAH HAGALR
//

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