(data stored in SCRATCH zone)

SWISSPROT: B2UHH8_RALPJ

ID   B2UHH8_RALPJ            Unreviewed;       493 AA.
AC   B2UHH8;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   RecName: Full=AMP nucleosidase {ECO:0000256|HAMAP-Rule:MF_01932};
DE            EC=3.2.2.4 {ECO:0000256|HAMAP-Rule:MF_01932};
GN   Name=amn {ECO:0000256|HAMAP-Rule:MF_01932};
GN   OrderedLocusNames=Rpic_3922 {ECO:0000313|EMBL:ACD29029.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29029.1, ECO:0000313|Proteomes:UP000002566};
RN   [1] {ECO:0000313|Proteomes:UP000002566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J {ECO:0000313|Proteomes:UP000002566};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the hydrolysis of the N-glycosidic bond of AMP
CC       to form adenine and ribose 5-phosphate. Involved in regulation of
CC       AMP concentrations. {ECO:0000256|HAMAP-Rule:MF_01932}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=AMP + H2O = adenine + D-ribose 5-phosphate;
CC         Xref=Rhea:RHEA:20129, ChEBI:CHEBI:15377, ChEBI:CHEBI:16708,
CC         ChEBI:CHEBI:78346, ChEBI:CHEBI:456215; EC=3.2.2.4;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01932};
CC   -!- SIMILARITY: Belongs to the AMP nucleosidase family.
CC       {ECO:0000256|HAMAP-Rule:MF_01932}.
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DR   EMBL; CP001069; ACD29029.1; -; Genomic_DNA.
DR   RefSeq; WP_004628021.1; NC_010678.1.
DR   STRING; 402626.Rpic_3922; -.
DR   EnsemblBacteria; ACD29029; ACD29029; Rpic_3922.
DR   GeneID; 6285101; -.
DR   KEGG; rpi:Rpic_3922; -.
DR   PATRIC; fig|402626.5.peg.161; -.
DR   eggNOG; ENOG4105FYV; Bacteria.
DR   eggNOG; COG0775; LUCA.
DR   HOGENOM; HOG000156781; -.
DR   KO; K01241; -.
DR   OMA; RPHAWIM; -.
DR   OrthoDB; 348840at2; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0008714; F:AMP nucleosidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0044209; P:AMP salvage; IEA:InterPro.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.1730.10; -; 1.
DR   Gene3D; 3.40.50.1580; -; 1.
DR   HAMAP; MF_01932; AMP_nucleosidase; 1.
DR   InterPro; IPR037109; AMP_N_sf.
DR   InterPro; IPR011271; AMP_nucleosidase.
DR   InterPro; IPR018953; AMP_nucleoside_Pase_N.
DR   InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR   InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR   PANTHER; PTHR43691:SF6; PTHR43691:SF6; 1.
DR   Pfam; PF10423; AMNp_N; 1.
DR   Pfam; PF01048; PNP_UDP_1; 1.
DR   SUPFAM; SSF53167; SSF53167; 1.
DR   TIGRFAMs; TIGR01717; AMP-nucleosdse; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2UHH8.
DR   SWISS-2DPAGE; B2UHH8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002566};
KW   Glycosidase {ECO:0000313|EMBL:ACD29029.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01932,
KW   ECO:0000313|EMBL:ACD29029.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002566}.
FT   DOMAIN       25    175       AMNp_N. {ECO:0000259|Pfam:PF10423}.
FT   DOMAIN      281    438       PNP_UDP_1. {ECO:0000259|Pfam:PF01048}.
SQ   SEQUENCE   493 AA;  55323 MW;  F2040B402EA92E8A CRC64;
     MTDTRATAHL YPAHDLAICT DANTAVERIT AIYERSAQAV RDRFHAFARG EDCSEDLSAC
     YPYLGITVDP KTLVSDARPA WGTVAYPGVY GTTLTRPDLF RDYYRVQIER LLHYHNSPVV
     VGVSNRPIPL PFVVEASTVD ITPEQARALG GAFTLPDLAQ IDDSIANGTY RPIGDEPQPL
     SMFTAERVDL ALQRLYHYTA THPKHFQRFV LFTNYQRYVD EFAALGRKLM EDGNDEGYIR
     FVEPGDTEHE LGTPAPDDSH RIKGLPQMPA YHLVREDRLG VTLVNIGVGP SNAKTITDHL
     AVLRPHCWMM IGHCGGLRRS QQLGDYVLAH AYVRDDHVLD QDLPPWVPVP PIAEIQVALQ
     EAVARITGLS GADMKSRMRT GTVVSTDDRN WELKYQALYS RFNQSRAIAI DMESATIAAN
     GFRLRVPYGT LLCVSDKPLH GELKLRGMAN LFYRQRVSQH LDIGMEAVRL LRESGVEALH
     SRKLRSFDEP AFR
//

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